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Anti-TROY Antibody (7B640)

😃Good
Catalog No. TMAY-02580
Alias tumor necrosis factor receptor superfamily, member 19, Troy, TRADE, TAJ-α, TAJ-ALPHA, TAJ, AW123854, AL023044

Anti-TROY Antibody (7B640) is a Mouse antibody targeting TROY. Anti-TROY Antibody (7B640) can be used in ELISA.

Anti-TROY Antibody (7B640)

Anti-TROY Antibody (7B640)

😃Good
Catalog No. TMAY-02580Alias tumor necrosis factor receptor superfamily, member 19, Troy, TRADE, TAJ-α, TAJ-ALPHA, TAJ, AW123854, AL023044
Anti-TROY Antibody (7B640) is a Mouse antibody targeting TROY. Anti-TROY Antibody (7B640) can be used in ELISA.
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100 μL$199 7-10 days
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Product Introduction

Bioactivity
Description
Anti-TROY Antibody (7B640) is a Mouse antibody targeting TROY. Anti-TROY Antibody (7B640) can be used in ELISA.
Aliastumor necrosis factor receptor superfamily, member 19, Troy, TRADE, TAJ-α, TAJ-ALPHA, TAJ, AW123854, AL023044
Ig Type
Monoclonal Mouse IgG1
Clone
7B640
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human TNFRSF19/TROY (rh TNFRSF19/TROY; TMPY-03571; Q9NS68-2; Met1-Leu170). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundTumor necrosis factor receptor superfamily, member 19 (TNFRSF19), also known as TAJ-alpha or TROY, is a member of the TNF-receptor superfamily. TNFRSF19/TROY expression is detected in the pulmonary epithelium and the ductal epithelium of the prostate and parotid glands. TNFRSF19/TROY expression is detected in some adenocarcinoma cell lines that arise from this tissue. It has been shown to interact with TRAF family members, and to activate JNK signaling pathway when overexpressed in cells. TNFRSF19/TROY is capable of inducing apoptosis by a caspase-independent mechanism, and it is thought to play an essential role in embryonic development. TNFRSF19/TROY was negatively regulated by adipogenic transcription factor CCAAT/enhancer-binding proteins (C/EBP). TNFRSF19 signals activation of the Jnk pathway and induces cell death. Overexpression of TNFRSF19 also signals NFB activation, comparable and similar to that by p75NGFR. TNFRSF19/TROY is capable of activating key signaling pathways of the TNF receptor family, and its predominant expression patterns suggest that it plays a role in the growth and regulation of epithelial tissues.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human TNFRSF19/TROY Protein (TMPY-03571)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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