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Anti-4-1BB Ligand/TNFSF9 Antibody-FITC (8F465)

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Catalog No. TMAY-03070F

Anti-4-1BB Ligand/TNFSF9 Antibody-FITC (8F465) is a FITC-conjugated Rabbit antibody targeting 4-1BB Ligand/TNFSF9. Anti-4-1BB Ligand/TNFSF9 Antibody-FITC (8F465) can be used in FCM.

Anti-4-1BB Ligand/TNFSF9 Antibody-FITC (8F465)

Anti-4-1BB Ligand/TNFSF9 Antibody-FITC (8F465)

😃Good
Catalog No. TMAY-03070F
Anti-4-1BB Ligand/TNFSF9 Antibody-FITC (8F465) is a FITC-conjugated Rabbit antibody targeting 4-1BB Ligand/TNFSF9. Anti-4-1BB Ligand/TNFSF9 Antibody-FITC (8F465) can be used in FCM.
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25 T$82 7-10 days
100 T$105 7-10 days
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Product Introduction

Bioactivity
Description
Anti-4-1BB Ligand/TNFSF9 Antibody-FITC (8F465) is a FITC-conjugated Rabbit antibody targeting 4-1BB Ligand/TNFSF9. Anti-4-1BB Ligand/TNFSF9 Antibody-FITC (8F465) can be used in FCM.
Ig Type
Monoclonal Rabbit IgG
Clone
8F465
Reactivity
Mouse
Verified Activity
Profile of anti-TNFSF9 reactivity on Raw264.7 cells analyzed by flow cytometry. Cells should be Fc-blocked by treatment with Mouse BD Fc Block™ purified anti-CD16/CD32 mAb 2.4G2 prior to staining, washed, then stained with FITC Rabbit anti-TNFSF9.
Application
FCM
Recommended Dose
10 μl/Test, 0.1 mg/ml
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse 4-1BBL / CD137L / TNFSF9 (rM 4-1BBL / CD137L / TNFSF9; TMPY-00959; NP_033430.1; Arg 104-Glu 309) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
PurificationProtein A
AppearanceLiquid
FormulationPBS solution containing 0.5% BSA and 0.09% sodium azide
Research Background4-1BB ligand is the high affinity ligand of 4-1BB, also known as CD137L or TNFSF9. It is shown to be a type II surface glycoprotein belonging to the TNF superfamily. Expression of 4-1BBL is restricted to APCs, such as dendritic cells, macrophages, and activated B cells. Members of the TNF-TNF receptor superfamily have been shown to play critical roles in regulating cellular activation, differentiation and apoptosis. Several studies have reported that 4-1BBL/4-1BB interaction provided a co-stimulatory signal to T cells, and increased T cell proliferation and cytokines production. In addition, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint TargetsImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
FITC
Others Formats
Unconjugated/APC/PerCP/PE
Antibody Types Available
5
Antigen Details
Immunogen
Recombinant Mouse 4-1BBL / CD137L / TNFSF9 protein (TMPY-00959)
Antigen Species
Mouse
Biology Area
Cancer Drug Targets
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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