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Anti-BAFFR/TNFRSF13C Antibody (2H990)

😃Good
Catalog No. TMAY-02814
Alias tumor necrosis factor receptor superfamily, member 13C, prolixin, CVID4, CD268, BROMIX, BAFF-R, BAFFR

Anti-BAFFR/TNFRSF13C Antibody (2H990) is a Mouse antibody targeting BAFFR/TNFRSF13C. Anti-BAFFR/TNFRSF13C Antibody (2H990) can be used in ELISA.

Anti-BAFFR/TNFRSF13C Antibody (2H990)

Anti-BAFFR/TNFRSF13C Antibody (2H990)

😃Good
Catalog No. TMAY-02814Alias tumor necrosis factor receptor superfamily, member 13C, prolixin, CVID4, CD268, BROMIX, BAFF-R, BAFFR
Anti-BAFFR/TNFRSF13C Antibody (2H990) is a Mouse antibody targeting BAFFR/TNFRSF13C. Anti-BAFFR/TNFRSF13C Antibody (2H990) can be used in ELISA.
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100 μL$199 7-10 days
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Product Introduction

Bioactivity
Description
Antibody Type: Mouse Monoclonal

Application: ELISA

Reactivity: Human
Aliastumor necrosis factor receptor superfamily, member 13C, prolixin, CVID4, CD268, BROMIX, BAFF-R, BAFFR
Ig Type
Mouse IgG1
Clone
2H990
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human BAFFR/TNFRSF13C (rh BAFFR/TNFRSF13C; TMPY-05060; NP_443177.1; Arg2-Ala71). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundTumor necrosis factor receptor superfamily, member 13C (TNFRSF13C) also known as B-cell-activating factor receptor (BAFFR) and CD268 antigen, is a member of the tumor necrosis factor receptor superfamily. A tumor necrosis factor receptor (TNFR), or death receptor, is a trimeric cytokine receptor that binds tumor necrosis factors (TNF). The receptor cooperates with an adaptor protein which is important in determining the outcome of the response. Members of the TNF receptor superfamily (TNFRSF) have crucial roles in both innate and adaptive immunity and in cellular apoptosis process. Apoptosis is a cell suicide mechanism that enables metazoans to control cell number in tissues and to eliminate individual cells that threaten the animal's survival. Certain cells have unique sensors, termed death receptors or tumour necrosis factor (TNFR), on their surface. Tumour necrosis factors (TNFR) detect the presence of extracellular death signals and, in response, they rapidly ignite the cell's intrinsic apoptosis machinery. It has been proposed that abnormally high levels of BAFFR/TNFRSF13C (CD268) may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human BAFFR/TNFRSF13C Protein (TMPY-05060)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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