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Anti-HGFR/c-Met Antibody (6F577)
😃Good
Catalog No. TMAY-03659
Alias MET proto-oncogene, receptor tyrosine kinase
Anti-HGFR/c-Met Antibody (6F577) is a Mouse antibody targeting HGFR/c-Met. Anti-HGFR/c-Met Antibody (6F577) can be used in ELISA.
Anti-HGFR/c-Met Antibody (6F577)
Anti-HGFR/c-Met Antibody (6F577)
😃Good
Catalog No. TMAY-03659Alias MET proto-oncogene, receptor tyrosine kinase
Anti-HGFR/c-Met Antibody (6F577) is a Mouse antibody targeting HGFR/c-Met. Anti-HGFR/c-Met Antibody (6F577) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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Antigen Details
Chemical Properties
| Description | Anti-HGFR/c-Met Antibody (6F577) is a Mouse antibody targeting HGFR/c-Met. Anti-HGFR/c-Met Antibody (6F577) can be used in ELISA. |
| Alias | MET proto-oncogene, receptor tyrosine kinase |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 6F577 |
| Reactivity | Canine |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Canine HGFR / c-MET (rCanine HGFR / c-MET; TMPY-02068; NP_001002963.1; Met 1-Leu 935). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that is overexpressed and/or mutated in a variety of malignancies. HGFR protein is produced as a single-chain precursor, and HGF is the only known ligand. Normal HGF/HGFR signaling is essential for embryonic development, tissue repair, or wound healing, whereas aberrantly active HGFR has been strongly implicated in tumorigenesis, particularly in the development of invasive and metastatic phenotypes. HGFR protein is a multifaceted regulator of growth, motility, and invasion, and is normally expressed by cells of epithelial origin. Preclinical studies suggest that targeting aberrant HGFR signaling could be an attractive therapy in cancer.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Canine HGFR / c-MET protein (TMPY-02068) |
| Antigen Species | Canine |
| Biology Area | Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs) |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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