Shopping Cart
- Remove All
Your shopping cart is currently empty
Anti-TRAIL/TNFSF10 Antibody (2R399)
😃Good
Catalog No. TMAY-00782
Alias tumor necrosis factor (ligand) superfamily, member 10
Anti-TRAIL/TNFSF10 Antibody (2R399) is a Mouse antibody targeting TRAIL/TNFSF10. Anti-TRAIL/TNFSF10 Antibody (2R399) can be used in ELISA,ELISA(Cap).
Anti-TRAIL/TNFSF10 Antibody (2R399)
Anti-TRAIL/TNFSF10 Antibody (2R399)
😃Good
Catalog No. TMAY-00782Alias tumor necrosis factor (ligand) superfamily, member 10
Anti-TRAIL/TNFSF10 Antibody (2R399) is a Mouse antibody targeting TRAIL/TNFSF10. Anti-TRAIL/TNFSF10 Antibody (2R399) can be used in ELISA,ELISA(Cap).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $69 | 7-10 days | |
| 100 μL | $198 | 7-10 days |
Bulk & Custom
Add to Cart
Questions
View MoreContact us for more batch information
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-TRAIL/TNFSF10 Antibody (2R399) is a Mouse antibody targeting TRAIL/TNFSF10. Anti-TRAIL/TNFSF10 Antibody (2R399) can be used in ELISA,ELISA(Cap). |
| Alias | tumor necrosis factor (ligand) superfamily, member 10 |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 2R399 |
| Reactivity | Human |
| Application | ELISA,ELISA(Cap) |
| Recommended Dose | ELISA: 1:1000-1:2000; ELISA(Cap): 1:250-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human TNFSF10 / TRAIL / APO-2L (CD253) (rh TNFSF10 / TRAIL / APO-2L (CD253); NP_003801.1Val114-Gly281). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Tumor necrosis factor ligand superfamily member 10 (TNFSF10), also known as TNF-related apoptosis-inducing ligand (TRAIL), Apo-2 ligand, and CD253, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. TNFSF10 / Apo-2L / CD253 functions as a ligand that induces the process of cell death called apoptosis. TNFSF10 / TRAIL shows homology to other members of the tumor necrosis factor superfamily. As one member of the cluster of differentiation system, TNFSF10 / CD253 is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion TNFSF10 / Apo-2L / CD253 / TRAIL binds to several members of TNF receptor superfamily including TNFRSF10A / TRAILR1, TNFRSF10B / TRAILR2, TNFRSF10C / TRAILR3, TNFRSF10D / TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of TNFSF10 / TRAIL may be modulated by binding to the decoy receptors TNFRSF10C / TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8 / JNK, caspase 8, and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human TNFSF10 / TRAIL / APO-2L (CD253) Protein |
| Antigen Species | Human |
| Biology Area | Cancer Drug Targets |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
Sci Citations
Calculator
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Anti-TRAIL/TNFSF10 Antibody (2R399) | purchase Anti-TRAIL/TNFSF10 Antibody (2R399) | Anti-TRAIL/TNFSF10 Antibody (2R399) cost | order Anti-TRAIL/TNFSF10 Antibody (2R399)
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.