Shopping Cart
- Remove All
Your shopping cart is currently empty
Anti-Tyrosine Hydroxylase Antibody (4U295)
😃Good
Catalog No. TMAY-03508
Alias tyrosine hydroxylase
Anti-Tyrosine Hydroxylase Antibody (4U295) is a Rabbit antibody targeting Tyrosine Hydroxylase. Anti-Tyrosine Hydroxylase Antibody (4U295) can be used in WB,ELISA.
Anti-Tyrosine Hydroxylase Antibody (4U295)
Anti-Tyrosine Hydroxylase Antibody (4U295)
😃Good
Catalog No. TMAY-03508Alias tyrosine hydroxylase
Anti-Tyrosine Hydroxylase Antibody (4U295) is a Rabbit antibody targeting Tyrosine Hydroxylase. Anti-Tyrosine Hydroxylase Antibody (4U295) can be used in WB,ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $268 | 7-10 days |
Bulk & Custom
Add to Cart
Questions
View MoreContact us for more batch information
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Tyrosine Hydroxylase Antibody (4U295) is a Rabbit antibody targeting Tyrosine Hydroxylase. Anti-Tyrosine Hydroxylase Antibody (4U295) can be used in WB,ELISA. |
| Alias | tyrosine hydroxylase |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 4U295 |
| Reactivity | Mouse |
| Verified Activity | Anti-TH rabbit monoclonal antibody at 1:500 dilution. -Lane A: PC12 Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:58 kDa. -Observed band size:63 kDa |
| Application | WB,ELISA |
| Recommended Dose | WB: 1:500-1:2000; ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse TH / Tyrosine Hydroxylase (TMPY-02587; P24529; Pro2-Ser498). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Tyrosine hydroxylase (TH) is a rate-limiting enzyme in catecholamine synthesis. Tyrosine hydroxylase activity is modulated by protein-protein interactions with enzymes in the same pathway or the tetrahydrobiopterin pathway, structural proteins considered to be chaperones that mediate the neuron's oxidative state, and the protein that transfers dopamine into secretory vesicles. It is phosphorylated at serine (Ser) residues Ser8, Ser19, Ser31 and Ser40 in vitro. The phosphorylation of tyrosine hydroxylase at Ser19 or Ser8 has no direct effect on tyrosine hydroxylase activity. As tyrosine hydroxylase (TH) catalyses the formation of L-DOPA, the rate-limiting step in the biosynthesis of DA, the Parkinson's disease (PD) can be considered as a TH-deficiency syndrome of the striatum. A direct pathogenetic role of TH has also been suggested, as the enzyme is a source of reactive oxygen species (ROS) in vitro and a target for radical-mediated oxidative injury. Recently, it has been demonstrated that L-DOPA is effectively oxidized by mammalian Tyrosine hydroxylase in vitro, possibly contributing to the cytotoxic effects of DOPA. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Mouse TH / Tyrosine Hydroxylase protein (TMPY-02587) |
| Antigen Species | Mouse |
| Biology Area | Neurotransmitter Associated Enzymes |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
Sci Citations
Calculator
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Anti-Tyrosine Hydroxylase Antibody (4U295) | purchase Anti-Tyrosine Hydroxylase Antibody (4U295) | Anti-Tyrosine Hydroxylase Antibody (4U295) cost | order Anti-Tyrosine Hydroxylase Antibody (4U295)
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.