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Anti-ROBO4 Antibody (6G423)
😃Good
Catalog No. TMAY-02167
Alias roundabout, axon guidance receptor, homolog 4 (Drosophila), Robo4, AI593217, 1200012D01Rik
Anti-ROBO4 Antibody (6G423) is a Rabbit antibody targeting ROBO4. Anti-ROBO4 Antibody (6G423) can be used in ELISA.
Anti-ROBO4 Antibody (6G423)
Anti-ROBO4 Antibody (6G423)
😃Good
Catalog No. TMAY-02167Alias roundabout, axon guidance receptor, homolog 4 (Drosophila), Robo4, AI593217, 1200012D01Rik
Anti-ROBO4 Antibody (6G423) is a Rabbit antibody targeting ROBO4. Anti-ROBO4 Antibody (6G423) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: ELISA Reactivity: Human |
| Alias | roundabout, axon guidance receptor, homolog 4 (Drosophila), Robo4, AI593217, 1200012D01Rik |
| Ig Type | Rabbit IgG |
| Clone | 6G423 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human ROBO4 (rh ROBO4; TMPY-02020; Q8WZ75-1; Met1-Glu469). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Roundabout homolog 4, also known as magic roundabout and ROBO4 is a member of the immunoglobulin superfamily and ROBO family. ROBO4 is specifically expressed in endothelial cells. It is expressed at sites of angiogenesis in different tumor types. ROBO4 contains two fibronectin type-III domains and two Ig-like C2-type (immunoglobulin-like) domains. ROBO4 is the fourth identified member of the roundabout receptor family. It is the only Robo family member expressed in primary endothelial cells and that application of Slit inhibits their migration. ROBO4 is predominantly expressed in embryonic or tumor vascular endothelium and is considered important for vascular development and as a candidate tumor endothelial marker. ROBO4 is a bona fide member of the Robo family and may provide a repulsive cue to migrating endothelial cells during vascular development. ROBO4 is a receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. ROBO4 may mediate the inhibition of primary endothelial cell migration by Slit proteins. Activating ROBO4 may have broad therapeutic application in diseases characterized by excessive angiogenesis and/or vascular leak. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human ROBO4 protein (TMPY-02020) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
Sci Citations
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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