Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-DDR2 Antibody (1R524)

😃Good
Catalog No. TMAY-03350
Alias TYRO10, TKT, NTRKR3, MIG20a, discoidin domain receptor tyrosine kinase 2, CD167

Anti-DDR2 Antibody (1R524) is a Rabbit antibody targeting DDR2. Anti-DDR2 Antibody (1R524) can be used in ELISA.

Anti-DDR2 Antibody (1R524)

Anti-DDR2 Antibody (1R524)

😃Good
Catalog No. TMAY-03350Alias TYRO10, TKT, NTRKR3, MIG20a, discoidin domain receptor tyrosine kinase 2, CD167
Anti-DDR2 Antibody (1R524) is a Rabbit antibody targeting DDR2. Anti-DDR2 Antibody (1R524) can be used in ELISA.
Pack SizePriceAvailabilityQuantity
20 μL$94 7-10 days
100 μL$268 7-10 days
Bulk & Custom
Add to Cart
Questions
View More
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Anti-DDR2 Antibody (1R524) is a Rabbit antibody targeting DDR2. Anti-DDR2 Antibody (1R524) can be used in ELISA.
AliasTYRO10, TKT, NTRKR3, MIG20a, discoidin domain receptor tyrosine kinase 2, CD167
Ig Type
Monoclonal Rabbit IgG
Clone
1R524
Reactivity
Mouse
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse DDR2 / CD167b (rM DDR2 / CD167b; TMPY-01728; NP_072075.2; Met1-Arg399).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundDiscoidin domain receptor 2 (DDR2) or CD167b (cluster of differentiation 167b) is a kind of protein tyrosine kinases associated with cell proliferation and tumor metastasis, and collagen, identified as a ligand for DDR2, up-regulates matrix metallloproteinase 1 (MMP-1) and MMP-2 expression in cellular matrix. DDR2/CD167b was found to recognise the triple-helical region of collagen X as well as the NC1 domain. Binding to the collagenous region was dependent on the triple-helical conformation. DDR2/CD167b autophosphorylation was induced by the collagen X triple-helical region but not the NC1 domain, indicating that the triple-helical region of collagen X contains a specific DDR2 binding site that is capable of receptor activation. DDR2/CD167b is induced during stellate cell activation and implicate the phosphorylated receptor as a mediator of MMP-2 release and growth stimulation in response to type I collagen. Moreover, type I collagen-dependent upregulation of DDR2/CD167b expression establishes a positive feedback loop in activated stellate cells, leading to further proliferation and enhanced invasive activity.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Mouse DDR2 / CD167b Protein (TMPY-01728)
Antigen Species
Mouse
Biology Area
Receptor Tyrosine Kinases (RTKs), Cancer Drug Targets
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

Sci Citations

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy Anti-DDR2 Antibody (1R524) | purchase Anti-DDR2 Antibody (1R524) | Anti-DDR2 Antibody (1R524) cost | order Anti-DDR2 Antibody (1R524)