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Methyl methanesulfonate

Name: Methyl methanesulfonate
Brand: TargetMol
SKU: T9985
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T9985Cas No. 66-27-3

Methyl methanesulfonate is a DNA alkylator that modifies adenine (3-methyladenine) and guanine (7-methyladenine) respectively, resulting in base mismatch and replication disorders.

Methyl methanesulfonate

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Purity: 99.69%

Catalog No. T9985Cas No. 66-27-3

Methyl methanesulfonate is a DNA alkylator that modifies adenine (3-methyladenine) and guanine (7-methyladenine) respectively, resulting in base mismatch and replication disorders.

Pack Size	Price	Availability	Quantity
10 g	$29	In Stock

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Batch Information

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Purity:99.69%

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COA HNMR

Product Introduction

Bioactivity

Description

Methyl methanesulfonate is a DNA alkylator that modifies adenine (3-methyladenine) and guanine (7-methyladenine) respectively, resulting in base mismatch and replication disorders.

Chemical Properties

Molecular Weight	110.13
Formula	C₂H₆O₃S
Cas No.	66-27-3
Smiles	O=S(=O)(OC)C

Storage & Solubility Information

Storage

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 60 mg/mL (544.81 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	9.0802 mL	45.4009 mL	90.8018 mL	454.0089 mL
5 mM	1.8160 mL	9.0802 mL	18.1604 mL	90.8018 mL
10 mM	0.9080 mL	4.5401 mL	9.0802 mL	45.4009 mL
20 mM	0.4540 mL	2.2700 mL	4.5401 mL	22.7004 mL
50 mM	0.1816 mL	0.9080 mL	1.8160 mL	9.0802 mL
100 mM	0.0908 mL	0.4540 mL	0.9080 mL	4.5401 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc