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Methyl methanesulfonate

Methyl methanesulfonate
Methyl methanesulfonate is a DNA alkylator that modifies adenine (3-methyladenine) and guanine (7-methyladenine) respectively, resulting in base mismatch and replication disorders.
Catalog No. T9985Cas No. 66-27-3
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Methyl methanesulfonate

Catalog No. T9985Cas No. 66-27-3
Methyl methanesulfonate is a DNA alkylator that modifies adenine (3-methyladenine) and guanine (7-methyladenine) respectively, resulting in base mismatch and replication disorders.
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Product Introduction

Bioactivity
Description
Methyl methanesulfonate is a DNA alkylator that modifies adenine (3-methyladenine) and guanine (7-methyladenine) respectively, resulting in base mismatch and replication disorders.
Chemical Properties
Molecular Weight110.13
FormulaC2H6O3S
Cas No.66-27-3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 60 mg/mL (544.81 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM9.0802 mL45.4009 mL90.8018 mL454.0089 mL
5 mM1.8160 mL9.0802 mL18.1604 mL90.8018 mL
10 mM0.9080 mL4.5401 mL9.0802 mL45.4009 mL
20 mM0.4540 mL2.2700 mL4.5401 mL22.7004 mL
50 mM0.1816 mL0.9080 mL1.8160 mL9.0802 mL
100 mM0.0908 mL0.4540 mL0.9080 mL4.5401 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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