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CAY10595

Name: CAY10595
Brand: TargetMol
SKU: T10691
Price: 46 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T10691Cas No. 916047-16-0

CAY10595 is an antagonist of the CRTh2 (DP2) receptor with a Ki of 10 nM.

CAY10595

🥰Excellent

Purity: 99.97%

Catalog No. T10691Cas No. 916047-16-0

CAY10595 is an antagonist of the CRTh2 (DP2) receptor with a Ki of 10 nM.

Pack Size	Price	Availability
1 mg	$46	In Stock
5 mg	$199	In Stock
10 mg	$349	In Stock
25 mg	$462	In Stock
50 mg	$690	In Stock
100 mg	$930	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.97%

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	CAY10595 is an antagonist of the CRTh2 (DP2) receptor with a Ki of 10 nM.
Targets&IC50	CRTH2/DP2 receptor:10 nM (ki)
In vivo	CAY10595 slightly delays the development of CIA and reduces IgG2a anti-CII levels without modification of the levels of IgG anti-CII[2].

Chemical Properties

Molecular Weight	451.23
Formula	C₂₀H₁₃Cl₂FN₂O₅
Cas No.	916047-16-0
Smiles	O=C1C2(C=3C(N1CC(O)=O)=CC=C(Cl)C3)C(=O)N(CC4=C(F)C=CC(Cl)=C4)C(=O)C2
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (110.81 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2162 mL	11.0808 mL	22.1616 mL	110.8082 mL
5 mM	0.4432 mL	2.2162 mL	4.4323 mL	22.1616 mL
10 mM	0.2216 mL	1.1081 mL	2.2162 mL	11.0808 mL
20 mM	0.1108 mL	0.5540 mL	1.1081 mL	5.5404 mL
50 mM	0.0443 mL	0.2216 mL	0.4432 mL	2.2162 mL
100 mM	0.0222 mL	0.1108 mL	0.2216 mL	1.1081 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc