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Tiliroside (Standard)
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Catalog No. TMSM-1424 Copy Product Info
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Tiliroside (Standard) is a reference standard for research and analytical applications involving Tiliroside. Tiliroside (Tribuloside) exhibits anticarcinogenic activity. Tiliroside demonstrates hepatoprotective activity. Tiliroside exhibits antioxidant and anti-inflammatory activity and can inhibit neuroinflammation in neurodegenerative disorder models. Tiliroside demonstrates anti-diabetic effects that are at least partially mediated through inhibitory effects on carbohydrate digestion and glucose uptake in the gastrointestinal tract. Tiliroside and gnaphaliin function as antioxidants against in vitro Cu(2+)-induced LDL oxidation in the same order of magnitude compared with the reference compound probucol. Tiliroside enhances fatty acid oxidation through enhancement of adiponectin signaling associated with activation of both AMP-activated protein kinase and peroxisome proliferator-activated receptor α and ameliorates obesity-induced metabolic disorders. Tiliroside (Standard) is therefore extensively applicable to metabolic, oxidative stress, inflammation, and natural product-based biomedical research.
Cas No. 20316-62-5
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 mg | $108 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Appearance:Solid
Color:White
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| Description | Tiliroside (Standard) is a reference standard for research and analytical applications involving Tiliroside. Tiliroside (Tribuloside) exhibits anticarcinogenic activity. Tiliroside demonstrates hepatoprotective activity. Tiliroside exhibits antioxidant and anti-inflammatory activity and can inhibit neuroinflammation in neurodegenerative disorder models. Tiliroside demonstrates anti-diabetic effects that are at least partially mediated through inhibitory effects on carbohydrate digestion and glucose uptake in the gastrointestinal tract. Tiliroside and gnaphaliin function as antioxidants against in vitro Cu(2+)-induced LDL oxidation in the same order of magnitude compared with the reference compound probucol. Tiliroside enhances fatty acid oxidation through enhancement of adiponectin signaling associated with activation of both AMP-activated protein kinase and peroxisome proliferator-activated receptor α and ameliorates obesity-induced metabolic disorders. Tiliroside (Standard) is therefore extensively applicable to metabolic, oxidative stress, inflammation, and natural product-based biomedical research. |
| In vitro | Tiliroside (100 μM, 30 min) inhibits rat peritoneal neutrophils’ enzymatic and non-enzymatic lipid peroxidation (IC50=12.6 and 28 μM, respectively) detected by MTT assay[1]. |
| In vivo | Tiliroside (50mg/kg; s.c.) significantly inhibits the mouse paw oedema induced by phospholipase A2 (ED50=35.6 mg/kg) and the mouse ear inflammation induced by TPA (500 to 250 Ag/ear). [1] |
| Molecular Weight | 594.52 |
| Formula | C30H26O13 |
| Cas No. | 20316-62-5 |
| Smiles | O(C1=C(OC=2C(C1=O)=C(O)C=C(O)C2)C3=CC=C(O)C=C3)[C@@H]4O[C@H](COC(/C=C/C5=CC=C(O)C=C5)=O)[C@@H](O)[C@H](O)[C@H]4O |
| Relative Density. | 1.68 g/cm3 (Predicted) |
| Storage | Keep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 µL Tween 80 and mix well until fully clarified.
3) Add 450 µL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: Tiliroside (Standard) chemical structure | Tiliroside (Standard) in vivo | Tiliroside (Standard) in vitro | Tiliroside (Standard) formula | Tiliroside (Standard) molecular weight
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