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Anti-GITR/TNFRSF18 Antibody (8L457) (Synonyms: tumor necrosis factor receptor superfamily, member 18, GITR-D, ...)

Catalog No. TMAY-02615 Copy Product Info
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Anti-GITR/TNFRSF18 Antibody (8L457) is a Rabbit antibody targeting GITR/TNFRSF18. Anti-GITR/TNFRSF18 Antibody (8L457) can be used in ELISA.

Anti-GITR/TNFRSF18 Antibody (8L457)

Copy Product Info
🥰Excellent
Catalog No. TMAY-02615
Synonyms tumor necrosis factor receptor superfamily, member 18, GITR-D, GITR, CD357, AITR

Anti-GITR/TNFRSF18 Antibody (8L457) is a Rabbit antibody targeting GITR/TNFRSF18. Anti-GITR/TNFRSF18 Antibody (8L457) can be used in ELISA.

Anti-GITR/TNFRSF18 Antibody
(8L457)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$2687-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-GITR/TNFRSF18 Antibody (8L457) is a Rabbit antibody targeting GITR/TNFRSF18. Anti-GITR/TNFRSF18 Antibody (8L457) can be used in ELISA.
Synonymstumor necrosis factor receptor superfamily, member 18, GITR-D, GITR, CD357, AITR
Ig Type
Rabbit IgG
Clone
8L457
Reactivity
Human
Specificity
Human GITR/TNFRSF18/AITR
Application
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human GITR/TNFRSF18/CD357 (rh GITR/TNFRSF18/CD357; TMPY-00072; NP_683700.1; Met1-Glu161).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundGITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. GITR may be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR and its ligand are important costimulatory molecules in the pathogenesis of autoimmune diseases. It also mediates NF-kappa-B activation via the TRAF2/NIK pathway.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint TargetsImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human GITR/TNFRSF18/CD357 Protein (TMPY-00072)
Antigen Species
Human
Biology Area
Cancer Drug Targets
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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