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Cat No. | Product Name | Synonyms | Targets |
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T37422L | Ras Inhibitory Peptide acetate | Ras Inhibitory Peptide acetate(159088-48-9 Free base) | Ras |
Ras Inhibitory Peptide acetate is a peptide involved in the Ras-dependent signaling pathway that plays an important role in human cancers initiated by oncogenic receptors. | |||
T16432 | Pan-RAS-IN-1 | MAPK , Ras | |
Pan-RAS-IN-1 is an inhibitor of pan-Ras. It disrupts the interaction of Ras proteins and their effectors. | |||
T5469 | K-Ras-IN-1 | Raf , Ras | |
K-Ras-IN-1 is a K-Ras inhibitor. | |||
T11738 | K-Ras G12C-IN-4 | Ras | |
K-Ras G12C-IN-4, is a potent Covalent Inhibitor of KRASG12C.. | |||
T6556 | K-Ras(G12C) inhibitor 9 | Raf | |
K-Ras(G12C) inhibitor 9 is an allosteric inhibitor of oncogenic K-Ras(G12C). | |||
T3725 | K-Ras(G12C) Inhibitor 6 | Raf | |
K-Ras(G12C) inhibitor 6 is an irreversible, allosteric inhibitor of the K-Ras(G12C) mutant that causes 100% modification of the protein when used at 10 μM for 24 hours in vitro. | |||
T6555 | K-Ras(G12C) inhibitor 12 | Apoptosis , Raf , Ras | |
K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C). | |||
T8659 | K-Ras-PDEδ-IN-1 | PDE | |
K-Ras-PDEδ-IN-1 is a potent inhibitor of competitive K-Ras-PDEδ.It binds to the farnesyl binding pocket of PDEδ(Kd of 8 nM). | |||
T12692 | RAS GTPase inhibitor 1 | Others | |
RAS GTPase inhibitor 1 is a inhibitor of RAS GTPase, with anti-tumor activity. | |||
T36642 | RAS/RAS-RAF-IN-1 | ||
RAS/RAS-RAF-IN-1 is a potent RAS and RAS-RAF inhibitor. RAS/RAS-RAF-IN-1 has a KD of 5.0 μμ-15 μμ for cyclophilin A (CYPA) binding affinity. RAS/RAS-RAF-IN-1 has antitumor activity[1]. RAS/RAS-RAF-IN-1 (compound 89; for ... | |||
T74698 | RMC-6236 | RAS-IN-2 | |
RMC-6236(RAS-IN-2) is a potent inhibitor of RAS(ON) MULTI, utilized in cancer research [1]. | |||
T36641 | RAS inhibitor Abd-7 | ||
RAS inhibitor Abd-7 is a powerful compound (Kd=51 nM) that binds to RAS and inhibits the protein-protein interaction (PPI) between RAS and its effectors. By interacting with RAS within cells, RAS inhibitor Abd-7 hinders ... | |||
T37422 | Ras Inhibitory Peptide | ||
Son of sevenless homolog 1 (Sos1) is a guanine nucleotide exchange factor (GEF) that directs the exchange of Ras-GDP to Ras-GTP by binding to SH3 domains of the growth factor receptor-bound protein 2 (Grb2), leading to t... | |||
T77800 | Ras inhibitor 134 | ||
T11735 | K-Ras G12C-IN-1 | Phosphatase | |
K-Ras G12C-IN-1 is a novel and irreversible inhibitor of mutant K-ras G12C. | |||
T11737 | K-Ras G12C-IN-3 | Others | |
Heterocyclic compounds as covalent inhibitors of G12C mutant K-Ras protein useful for treating cancers.K-Ras G12C-IN-3 is a novel and irreversible inhibitor of mutant K-ras G12C. | |||
T11736 | K-Ras G12C-IN-2 | Others | |
K-Ras G12C-IN-2 is a covalent kras g12c inhibitor. | |||
T13844 | PROTAC K-Ras Degrader-1 | Ras | |
PROTAC K-Ras Degrader-1 is potent degrader of K-Ras based PROTAC. | |||
T18059 | K-Ras ligand-Linker Conjugate 6 | Others | |
K-Ras ligand-Linker Conjugate 6 is a chemical compound that combines a ligand for K-Ras recruiting moiety and a PROTAC linker. This compound can recruit E3 ligases, including VHL, CRBN, MDM2, and IAP. K-Ras ligand-Linker... | |||
T18058 | K-Ras ligand-Linker Conjugate 5 | Others | |
K-Ras ligand-Linker Conjugate 5 is a chemical compound that combines a ligand for the K-Ras recruiting moiety with a PROTAC linker. This linker is responsible for recruiting E3 ligases such as VHL, CRBN, MDM2, and IAP. T... | |||
T18055 | K-Ras ligand-Linker Conjugate 2 | Others | |
K-Ras ligand-Linker Conjugate 2 is a chemical compound that includes a ligand for K-Ras and a PROTAC linker. This compound is capable of recruiting E3 ligases like VHL, CRBN, MDM2, and IAP. It is utilized in the synthesi... | |||
T18057 | K-Ras ligand-Linker Conjugate 4 | Others | |
K-Ras ligand-Linker Conjugate 4 is a chemical compound that combines a ligand for K-Ras recruiting moiety with a PROTAC linker. This linker is responsible for recruiting E3 ligases such as VHL, CRBN, MDM2, and IAP. The c... | |||
T18054 | K-Ras ligand-Linker Conjugate 1 | Others | |
K-Ras ligand-Linker Conjugate 1 is a chemical compound that includes a ligand for K-Ras and a PROTAC linker, facilitating the recruitment of E3 ligases VHL, CRBN, MDM2, and IAP. It can be utilized in the synthesis of PRO... | |||
T18056 | K-Ras ligand-Linker Conjugate 3 | Others | |
K-Ras ligand-Linker Conjugate 3 (Compound 001371) is a chemical compound that consists of a ligand for K-Ras recruiting moiety and a PROTAC linker, responsible for recruiting E3 ligases (e.g., VHL, CRBN, MDM2, and IAP). ... | |||
T72774 | Ras modulator-1 | ||
Ras modulator-1 is a modulator of Ras. | |||
T1931 | 6H05 | K-Ras inhibitor | Raf , Ras |
6H05 (K-Ras inhibitor) is a selective, allosteric inhibitor of oncogenic mutant K-Ras(G12C). | |||
T39099 | G12 | Ras 5-17 | |
G12 (Ras 5-17) is a wild-type Ras peptide composed of amino acids 5-17, specifically KLVVVGAGGVGKS. It can serve as a control in studies focused on mutant Ras peptides, like V12. | |||
T1892 | Kobe2602 | Raf , Ras | |
Kobe 2602 is an inhibitor of Ras that exhibits anticancer chemotherapeutic activities. | |||
T6462 | Deltarasin | PDE , Ras | |
Deltarasin is a small molecular inhibitor of KRAS-PDEδ interaction with Kd of 38 nM for binding to purified PDEδ. | |||
T4370 | Resminostat hydrochloride | 4SC-201 hydrochloride,RAS2410 hydrochloride | HDAC |
Resminostat hydrochloride (RAS2410 hydrochloride) is an effective inhibitor of HDAC1/HDAC3/HDAC6 (IC50: 42.5/50.1/71.8 nM), respectively, and shows less potent activities against HDAC8 (IC50: 877 nM). | |||
T1876 | Kobe0065 | Apoptosis , Raf , Ras | |
Kobe0065 is a novel and effective small-molecule compound inhibiting Ras–Raf interaction by SBDD; shows potent activity to competitively inhibit the binding of H-Ras·GTP to c-Raf-1 RBD with a Ki value of 46 ± 13 μM. | |||
T9407 | Rasarfin | Others , Ras | |
Rasarfin inhibits Ras and ARF6. | |||
T9986 | (E/Z)-ZINC09659342 | Rho | |
(E/Z)-ZINC09659342 is an inhibitor of Lbc-Rho A interaction. | |||
T2678 | LB42708 | Transferase | |
LB42708 is an orally active farnesyltransferase (FTase) inhibitor (IC50: 0.8/1.2/2.0 nM toward H/N/K-ras). | |||
T60029 | SOS1-IN-11 | Raf | |
SOS1-IN-11 is an effective inhibitor of SOS1 (IC50 = 30 nM). | |||
T20759 | XRP44X | XRP-44-X,XRP 44X,XRP-44X,XRP 44 X | Ras |
XRP44X (XRP 44X) is a potent inhibitor of Ras-Net (Elk-3) pathway. | |||
T2267 | BQU57 | GTPase , Ras | |
BQU57 shows selective inhibition for Ral relative to Ras or Rho and inhibit xenograft tumor growth. | |||
T10533 | BI-2852 | Ras | |
BI-2852 is a KRAS inhibitor for the switch I/II pocket (SI/II-pocket) with nanomolar affinity. BI-2852 is leading to inhibition of downstream signaling and an antiproliferative effect in KRAS mutant cells. | |||
T5597 | ZT-12-037-01 | Serine Protease , Ras | |
Zt-12-037-01 is a ATP competitive STK19 inhibitor(IC50 values of 23.96 nM and 27.94 nM for STK19 (WT) and STK19 (D89N),respectively). | |||
T38050 | CP-609754 | Transferase | |
CP-609754 (LNK-754) is a potent and reversible farnesyltransferase inhibitor with potential anticancer activity.The IC50 for inhibiting farnesylation of recombinant human H-Ras is 0.57 ng/mL and recombinant K-Ras is 46 n... | |||
T10375 | ARS-1323 | Ras | |
ARS-1323 is the racemate of ARS-1620 and a mutant K-ras G12C inhibitor. | |||
T10376 | ARS-1630 | Ras | |
ARS-1630 is a mutant K-ras G12C inhibitor. It is a less active enantiomer of ARS-1620. | |||
T6634 | RBC8 | GTPase , Ras | |
RBC8 is a specific GTPases RalA/RalB inhibitor by inhibiting the binding of Ral to its effector RALBP1, no inhibition on the GTPases RhoA and Ras. | |||
T3553 | Y16 | Rho , Ras | |
Y16 is a G-protein–coupled Rho GEFs inhibitor; works synergistically with Rhosin/G04 in inhibiting LARG-RhoA interaction, RhoA activation, and RhoA-mediated signaling functions. | |||
T5418 | BAY-293 | Raf , Ras | |
BAY-293 is a potent, cell-active SOS1 inhibitor that disrupts the KRAS-SOS1 interaction (IC50: 21 nM). | |||
T7609 | ARS-1620 | Ras | |
ARS-1620 is a covalent inhibitor of K-RASG12C. | |||
T39738 | ASP2453 | Ras | |
ASP2453 is a potent, selective and covalent inhibitor of KRAS G12C. ASP2453 inhibits the Son of Sevenless (SOS)-mediated interaction between KRAS G12C and Raf with an IC50 value of 40 nM. | |||
T8006 | Oncrasin-1 | Apoptosis , Raf , Ras | |
Oncrasin 1 is a potent inhibitor of anticancer that kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrations | |||
T14004 | 1A-116 | Rho | |
1A-116 is a specific inhibitor of Rac1 . | |||
T8473 | MLS000532223 | Rho , Ras | |
MLS000532223 is a selectiveRho family GTPases inhibitor(EC50 : 16 μM to 120 μM). |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T5S1261 | Methylophiopogonanone B | Ras | |
1. Methylophiopogonanone B (MOPB) induces cell morphological change and Rho activation via melanocyte dendrite retraction and stress fiber formation. | |||
T5S0777 | Phellodendrine chloride | Others | |
Phellodendrine chloride has anti-nephritic activity, may be due to its ability to inhibit the proliferation or the migration of macrophages and cytotoxic T lymphocytes in the glomeruli. | |||
T5368 | Eicosapentaenoic Acid | Histone Demethylase , Others , Endogenous Metabolite | |
Eicosapentaenoic Acid (EPA) is a ω-3 fatty acid abundantly available in marine organisms. | |||
TQ0165 | Arglabin | (+)-Arglabin | NOD-like Receptor (NLR) , Transferase , NOD , Autophagy |
Arglabin ((+)-Arglabin) is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects. | |||
TN1413 | Atranorin | Endogenous Metabolite , NO Synthase , Ras | |
Atranorin shows significant antinociceptive and antiinflammatory activities, it has a relevant redox-active action, acting as a pro-oxidant or antioxidant agent depending on the radical, also, it will exert cytoprotectiv... | |||
T7131 | Antineoplaston A10 | NSC-648539 | Apoptosis , Endogenous Metabolite , Ras |
Antineoplaston A10 (NSC-648539) is a Ras inhibitor potentially for the treatment of glioma, lymphoma, astrocytoma and breast cancer. | |||
T7132 | (Rac)-Brassinazole | BRASSINAZOLE | P450 |
(Rac)-Brassinazole are a class of phytohormones with essential roles in plant growth and development, including the promotion of stem elongation and cell division. Brassinazole is a triazole-type brassinosteroid biosynth... | |||
T8244 | Raspberry ketone glucoside | Others | |
Raspberry ketone glucoside is a natural product in raspberry fruit, has lasting effects for the inhibition of melanogenesis and various melanogenic factors after the degradation in the skin. | |||
T5514 | Epibrassinolide | 24-Epibrassinolide,B1105,BP55 | Apoptosis |
Epibrassinolide (BP55) (EBR) is a biologically active compound of the brassinosteroids, is a natural brassinosteroid (BR) derivative, is a plant regulator with a similar structure to mammalian steroids. | |||
T15753 | Licraside | Licuraside | Tyrosinase |
Licraside is a tyrosinase inhibitor with an IC50 of 0.072 mM for monophenolase and can be used in studies about antibrowning and depigmenting agents. | |||
T3151 | Brassinolide | Brassin lactone,24-Epibrassinolide | Apoptosis , Others |
Brassinolide (Brassin lactone) is a plant hormone isolated from rapeseed (Brassica napus) promoting stem elongation and cell division. | |||
TQ0160 | Hydrastine | (-)-β-Hydrastine,(1R,9S)-β-Hydrastine | Others |
Hydrastine ((-)-β-Hydrastine) is a natural alkaloid that is present in Hydrastis Canadensis. | |||
T4373 | Brassinin | BSN | Antifungal |
Brassinin (BSN) (BSN) is a phytoalexin isolated from B. campestris that exhibits anticancer, chemopreventative, antiproliferative, and antifungal activities. | |||
T41372 | (22S,23S)-Homobrassinolide | SSHB | Others |
(22S,23S)-Homobrassinolide (SSHB) induces plant growth in various plant bioassay systems. | |||
T2S0633 | Raspberry ketone | Oxyphenalon,Rasketone,Aloenin,4-(4-Hydroxyphenyl)-2-butanone,p-Hydroxybenzyl acetone,Frambinone | PPAR |
1. Raspberry ketone (p-Hydroxybenzyl acetone) is cytotoxic to melanocytes through the binding of RK-derived quinones to thiol proteins and the pro-oxidant activity of the RK-oligomer, the exposure of human skin to RK can... | |||
T4S1114 | Dryocrassin ABBA | Dryocrassin | Influenza Virus , Antibacterial |
Dryocrassin ABBA (Dryocrassin) is a flavonoid natural product derived from Dryopteris crassirhizoma, with antiviral and antibacterial activities. | |||
T3345 | Hederasaponin B | Eleutheroside M,Hederacoside B | Others , Virus Protease |
Hederasaponin B (Hederacoside B) has antiviral activity, via inhibiting the viral VP2 protein expression and blocking viral capsid protein synthesis. | |||
T3S1892 | Crassicauline A | Crassicauline I | Others |
1. Crassicauline A (Crassicauline I) and Yunaconitine possesses feeding deterrent activity against T. castaneum adults, with EC(5) values of 1134.5 and 653.4 ppm, respectively. | |||
TN7077 | Sinocrassoside C1 | Others | |
Sinocrassoside C1 is the methanolic extract of the whole plant of Sinocrassula indica (Crassulaceae), six new flavonol glycosides | |||
TN3142 | 6,11-Di-O-acetylalbrassitriol | Others | |
6,11-Di-O-acetylalbrassitriol is a natural product for research related to life sciences. The catalog number is TN3142 and the CAS number is 110538-20-0. | |||
T2S0799 | Noroxyhydrastinine | Tyrosinase | |
Noroxyhydrastinine exhibits potent melanogenesis-inhibitory activities, it inhibits melanogenesis, at least in part, by inhibiting the expression of protein levels of tyrosinase, TRP-1, and TRP-2 in α-MSH-stimulated B16 ... | |||
TN3163 | 6-epi-Albrassitriol | Others | |
6-epi-Albrassitriol is a natural product from A spergillussp. | |||
TN3717 | Crassanine | Others | |
Crassanine is a natural product for research related to life sciences. The catalog number is TN3717 and the CAS number is 16790-92-4. | |||
TN6651 | Picrasidine Q | ||
Picrasidine Q has the capacity of anti-cell transformation and anti-cancer, it might be a chemopreventive and chemotherapeutic agent by direct targeting FGFR2 and inhibiting cell proliferation of ESCC cells. | |||
T75503 | 2-Hydroxyalbrassitriol | ||
2-Hydroxyalbrassitriol (Compound 6) is an AChE inhibitor with an IC 50 of 35.97 μM [1] . | |||
T13082 | Tarasaponin VI | Others | |
Tarasaponin VI is isolated from Aralia elata with potent inhibitory activity on ethanol absorption. | |||
T21577 | Narasin (sodium salt) | Naracin sodium salt,naransin sodium,HainanMycin | NF-κB |
Narasin (sodium salt) (HainanMycin) induces tumor necrosis factor-related apoptosis-induced ligand (TRAIL)-mediated apoptosis by ER stress in glioma cells and inhibits NF-κB signaling by suppressing the phosphorylation o... | |||
T83134 | Alterbrassicene B | ||
Alterbrassicene B, an anticancer agent, is isolatable from the fungus Alternaria brassicicola [1]. | |||
T28415 | Picrasidine N | Picrasidine-N,PicrasidineN | |
Picrasidine N is a naturally occurring dimeric alkaloid and a PPARβ/δ agonist. | |||
T1607 | Hydrastinine hydrochloride | Others | |
Hydrastinine hydrochloride is a semisynthetic alkaloid from the hydrolysis of the alkaloid Hydrastine, used as a haemostatic drug. | |||
T40758 | Hydrastinine | ||
Hydrastinine, a key alkaloid component found in Hydrastis canadensis (goldenseal), serves as an effective hemostatic agent. | |||
TN5366 | 12-Hydroxyalbrassitriol | ||
12-Hydroxyalbrassitriol is a natural product for research related to life sciences. The catalog number is TN5366 and the CAS number is 2193060-23-8. | |||
TN2597 | 12-Hydroxy-6-epi-albrassitriol | Others | |
12-Hydroxy-6-epi-albrassitriol is a natural product for research related to life sciences. The catalog number is TN2597 and the CAS number is 178330-78-4. | |||
TN4392 | Koaburaside | IL Receptor , TNF , Influenza Virus | |
Koaburaside exhibits antioxidant activity with an IC50 value of 9.0μM, it shows weak inhibitory activity against influenza A neuraminidase. Koaburaside may have anti-allergic inflammatory activity, it can suppress histam... | |||
TN4393 | Koaburaside monomethyl ether | Others | |
Koaburaside monomethyl ether is a natural product of Croton, Euphorbiaceae. The catalog number is TN4393 and the CAS number is 41514-64-1. Koaburaside monomethyl ether can be used as a reference standard. | |||
T8465 | 28-high brassinolide | ||
28-high brassinolide is a natural product for research related to life sciences. The catalog number is T8465 and the CAS number is 82373-95-3. | |||
TN1450 | Brassicasterol | 油菜 | Others |
Brassicasterol may be a relevant additional biomarker in Alzheimer's disease (AD). | |||
TN4924 | Rubiprasin A | Others | |
Rubiprasin A is a natural product from Rubia cordifolia var. pratensis. | |||
T24638 | Picrasidine M | ||
Picrasidine M is a PARP-1 inhibitor. | |||
TN3051 | 4-Methoxyglucobrassicin | Others | |
4-Methoxyglucobrassicin is a natural product for research related to life sciences. The catalog number is TN3051 and the CAS number is 83327-21-3. | |||
T27281 | Eritoran Tetrasodium | B 1287,E 5564,B-1287,E5564,B1287,E-5564 | |
Eritoran Tetrasodium, a TLR4 receptor antagonist, is used potentially for the treatment of type 2 diabetes. | |||
TN4925 | Rubiprasin B | Others | |
Rubiprasin B is a natural product from Rubia cordifolia var. pratensis. | |||
TN1796 | Brassicin | Isorhamnetin 7-O-glucoside | Others |
Isorhamnetin 7-O-glucoside has antioxidant activity, it showed the peroxynitrite and DPPH scavenging activities with IC50 values of 2.07 /- 0.17 and 13.3 microM, respectively. | |||
TN3373 | Albrassitriol | Others | |
Albrassitriol is a natural product from the cultures of the fungus Penicillium sp. | |||
TN5387 | Grasshopper ketone | ERK , p38 MAPK , NO Synthase , JNK | |
Grasshopper ketone, isolated from the brown alga Sargassum, is a potent inhibitor of LPS-induced NO production in RAW 264.7 cells and induces anti-inflammatory effects by inhibiting MAPK (ERK, JNK and p38) and NF-κB p65 ... | |||
TN4786 | Picrasin B acetate | Others | |
Picrasin B acetate is a natural product for research related to life sciences. The catalog number is TN4786 and the CAS number is 30315-04-9. | |||
TN6010 | Picrasidine S | ||
Picrasidine S shows the potent cytotoxicity against human HeLa cervical, gastric MKN-28, and mouse melanoma B-16 cancer cells, it also shows the potent antibacterial activity against two strains of pathogenic bacteria me... | |||
TN3593 | Carasiphenol C | Others | |
Carasiphenol C is a natural product from Carex humilis Leyss. | |||
T38038 | (-)-Rasfonin | ||
(-)-Rasfonin is a fungal metabolite that has been found in T. terrophilus.1 It inhibits proliferation of mouse splenocytes induced by concanavalin A and LPS (IC50s = 0.7 and 0.5 μg/ml, respectively). References1. Fujimot... | |||
T82822 | Brassicanate A sulfoxide | ||
Brassicanate A sulfoxide, isolated from Brassica oleracea [1], exhibits herbicidal properties by inhibiting the biosynthesis of essential amino acids in plants. It operates by binding to key enzymes such as dihydroxyacid... | |||
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Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04116 | KRAS Protein,Human,Recombinant(G12C & Q61H, His) | Human | E. coli |
K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec... | |||
TMPY-04113 | KRAS Protein,Human,Recombinant(G12D & Q61H, His) | Human | E. coli |
K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec... | |||
TMPY-01888 | KRAS Protein,Human, Recombinant (Q61H, His) | Human | E. coli |
K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec... | |||
TMPY-06056 | KRAS Protein, Human, Recombinant (G12D, His) | Human | E. coli |
K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec... | |||
TMPY-03487 | NRAS Protein, Human, Recombinant (His) | Human | E. coli |
NRAS was discovered by researchers at the Institute of Cancer Research, funded by the Cancer Research Campaign (now Cancer Research UK). NRAS gene is a member of the Ras gene family. It is mapped on chromosome 1, and it ... | |||
TMPJ-00510 | KRAS Protein, Human, Recombinant (G12C, His) | Human | E. coli |
K-Ras belongs to the small GTPase superfamily, Ras family. As other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes becau... | |||
TMPJ-00511 | KRAS Protein, Human, Recombinant (G12V, His) | Human | E. coli |
K-Ras belongs to the small GTPase superfamily, Ras family. As other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes becau... | |||
TMPY-04203 | RAB1B Protein, Human, Recombinant (hFc) | Human | HEK293 |
RAB1B, a member of the RAS oncogene family, was significantly down-regulated in highly metastatic breast cancer cells. Moreover, down-regulation of RAB1B was also found to promote the proliferation and migration of TNBC ... | |||
TMPY-03813 | RAB27B Protein, Human, Recombinant (His) | Human | HEK293 |
RAB27B is a member of the Rab family GTPases involved in vesicle trafficking. The Rab27 subfamily consists of Rab27a and Rab27b. The human RAB27B gene is organized in six exons, spanning about 69 kb in the chromosome 18q... | |||
TMPY-04112 | RAB31 Protein, Human, Recombinant (His) | Human | E. coli |
TMPY-04152 | RAB7A Protein, Rat, Recombinant (His) | Rat | E. coli |
RAB7A is a ubiquitous small GTPase, which controls transport to late endocytic compartments. Silencing or overexpression of wild type RAB7A changed the soluble/insoluble rate of peripherin indicating that RAB7A is import... | |||
TMPY-03430 | RheB Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
RHEB is a recently discovered member of the Ras superfamily that may be involved in neural plasticity. This function is novel and not typically associated with the Ras proteins. RHEB gene is a member of the small GTPase ... | |||
TMPY-00490 | RAB6A Protein, Human, Recombinant (His) | Human | E. coli |
Rab6 is one of the most conserved Rab GTPaes throughout evolution and the most abundant Rab protein associated with the Golgi complex. The two ubiquitous Rab isoforms, Rab6A and Rab6A', that are generated by alternative ... | |||
TMPY-04059 | RAB27B Protein, Human, Recombinant | Human | HEK293 |
RAB27B is a member of the Rab family GTPases involved in vesicle trafficking. The Rab27 subfamily consists of Rab27a and Rab27b. The human RAB27B gene is organized in six exons, spanning about 69 kb in the chromosome 18q... | |||
TMPY-04311 | RAB11B Protein, Human, Recombinant (His) | Human | HEK293 |
The two recurrent dominant mutations in RAB11B leading to a neurodevelopmental syndrome, likely caused by altered GDP/GTP binding that inactivate the protein and induce GEF binding and protein mislocalization. | |||
TMPU-00001 | KRAS Protein, Human, Recombinant (G12S, GST) | Human | E. coli |
K-Ras belongs to the small GTPase superfamily, Ras family. As other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes becau... | |||
TMPY-04026 | RAB27B Protein, Human, Recombinant (mFc) | Human | HEK293 |
RAB27B is a member of the Rab family GTPases involved in vesicle trafficking. The Rab27 subfamily consists of Rab27a and Rab27b. The human RAB27B gene is organized in six exons, spanning about 69 kb in the chromosome 18q... | |||
TMPY-06345 | KRAS Protein, Human, Recombinant (His & Avi), Biotinylated | Human | E. coli |
K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec... | |||
TMPY-00610 | RAB2 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
RAB2A, a protein essential for ER-to-Golgi transport, is critical in promoting proteolytic activity and 3D invasiveness of breast cancer (BC) cell lines.RAB2A is amplified and elevated in human BC and is a powerful and i... | |||
TMPY-06138 | KRAS Protein, Human, Recombinant (61Q, His) | Human | E. coli |
K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec... | |||
TMPJ-01126 | RheB Protein, Human, Recombinant (GST) | Human | E. coli |
GTP-Binding Protein Rheb (RHEB) is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. Highest levels of RHEB can be foun... | |||
TMPY-03979 | ARHI Protein, Human, Recombinant (mFc) | Human | HEK293 |
ARHI, also known as DIRAS3, belongs to the small GTPase superfamily, Di-Ras family. ARHI gene is a novel tumor suppressor gene located on chromosome 1p31. Downregulation of ARHI expression has been detected in many types... | |||
TMPY-01958 | RhoA Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Transforming protein RhoA, also known as Rho cDNA clone 12, Ras homolog gene family member A, RHOA and ARH12, is a cell membrane and cytoplasm protein that belongs to the small GTPase superfamily and Rho family. The Rho ... | |||
TMPY-02220 | HRAS Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
HRas, also known as HRAS, belongs to the small GTPase superfamily, Ras family, and is widely expressed. It functions in signal transduction pathways. HRas can bind GTP and GDP, and they have intrinsic GTPase activity. It... | |||
TMPY-01187 | Rac1 Protein, Human, Recombinant (GST) | Human | Baculovirus-Insect Cells |
RAC1 is a GTPase that belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal re... | |||
TMPY-02439 | Rac2 Protein, Human, Recombinant (His) | Human | E. coli |
Ras-related C3 botulinum toxin substrate 2 (Rac2) is a small G-protein belonging to the Ras subfamily of the GTPase family. Rac2 acts as an "on / off" switch for signal transduction cascades and motilities. When GDP is a... | |||
TMPY-00690 | Carbonic Anhydrase 9 Protein, Human, Recombinant (His) | Human | HEK293 |
Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzym... | |||
TMPY-01735 | Carbonic Anhydrase 2 Protein, Human, Recombinant (His) | Human | E. coli |
The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bi... | |||
TMPY-00689 | Carbonic Anhydrase 9 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzym... | |||
TMPY-00694 | Carbonic Anhydrase 12 Protein, Human, Recombinant (His) | Human | HEK293 |
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological processes, including respi... | |||
TMPY-01776 | Carboxylesterase 2/CES2 Protein, Human, Recombinant (His) | Human | HEK293 |
Carboxylesterase 2 (CES2) is a member of the carboxylesterase family and belongs to the multigene family. Carboxylesterase 2 is responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and... | |||
TMPY-06936 | Carbonic Anhydrase 9 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzym... | |||
TMPY-00279 | Dengue virus DENV-2 (strain New Guinea C) NS5 (methyltransferase domain)/Nonstructural protein 5 Protein (His) | DENV | E. coli |
TMPY-01700 | Carbonic Anhydrase 9 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzym... | |||
TMPY-02990 | Carbonic Anhydrase 9 Protein, Canine, Recombinant (His) | Canine | HEK293 |
Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzym... | |||
TMPY-01690 | Carboxylesterase 2/CES2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Carboxylesterase 2 (CES2) is a member of the carboxylesterase family and belongs to the multigene family. Carboxylesterase 2 is responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and... | |||
TMPY-02301 | Carbonic Anhydrase 8 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bi... | |||
TMPY-06939 | Carbonic Anhydrase 9 Protein, Human, Recombinant (hFc & Avi), Biotinylated | Human | HEK293 |
Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzym... | |||
TMPY-02133 | Carbonic Anhydrase VB Protein, Human, Recombinant (His) | Human | E. coli |
Carbonic anhydrase 5B, also known as carbonate dehydratase VB, carbonic anhydrase VB, CA-VB and CA5B, is amember of the alpha-carbonic anhydrase family. The strongest expression of CA5B / CA-VB is in heart, pancreas, ... | |||
TMPY-00693 | Carbonic Anhydrase 10 Protein, Human, Recombinant | Human | HEK293 |
Carbonic anhydrase X, also called carbonic anhydrase - related protein X (CARPX) and CA1, belongs to the CA family of zinc metalloenzymes which catalyze the reversible hydration of carbon dioxide in various biological pr... | |||
TMPY-03445 | Aspartate Aminotransferase Protein, Human, Recombinant (His) | Human | E. coli |
GOT1 (Glutamic-Oxaloacetic Transaminase 1) is a Protein Coding gene. GOT1 belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent... | |||
TMPY-01761 | Carbonic Anhydrase 3 Protein, Human, Recombinant (His) | Human | E. coli |
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological processes, including re... | |||
TMPY-01706 | Carbonic Anhydrase 8 Protein, Human, Recombinant (His) | Human | E. coli |
The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bi... | |||
TMPY-05673 | Human coronavirus (HCoV-OC43) Hemagglutinin esterase Protein (His) | HCoV-OC43 | HEK293 |
TMPJ-00606 | Leptin Protein, Carassius auratus, Recombinant (His) | Carassius auratus | Yeast |
Leptin is a hormone secreted from white adipocytes and plays important role in the regulation of food intake and energy balance. Leptin functions via signaling pathways involving OB-R in hypothalamus. In mammals, leptin ... | |||
TMPJ-01429 | SARS-CoV-2 Guanine-N7 methyltransferase Protein (His) | SARS-CoV-2 | E. coli |
The nonstructural protein (nsp) 14 of SARS-CoV 2 was identified as a cap (guanine-N7)-methyltransferase (N7-MTase). Nsp14 of coronaviruses two different activities: an exoribonuclease activity acting on both ssRNA and ds... | |||
TMPH-03424 | Rotavirus A (strain Nebraska calf diarrhea virus) VP4 Protein (His & Myc) | RV-A | E. coli |
Spike-forming protein that mediates virion attachment to the host epithelial cell receptors and plays a major role in cell penetration, determination of host range restriction and virulence. Rotavirus attachment and entr... | |||
TMPH-03259 | Carbonic Anhydrase 2 Protein, Rat, Recombinant (His) | Rat | E. coli |
Essential for bone resorption and osteoclast differentiation. Reversible hydration of carbon dioxide. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide abso... | |||
TMPH-01418 | KRAS Protein, Human, Recombinant (His) | Human | E. coli |
KRAS Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPH-00557 | DXP reductoisomerase Protein, E. coli, Recombinant (His & Myc) | E. coli | E. coli |
Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP). | |||
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A unique collection of 253 natural products with antiparasitic activity, a powerful tool for high throughput screening (HTS) and high content screening (HCS); | |||
L4510 | Anti-Parasitic Compound Library | 420 compounds | |
420 well-chosen unique anti-parasitic small molecules; | |||
L8700 | Ferroptosis Compound Library | 800 compounds | |
A unique collection of 800 ferroptosis signaling pathway related compounds, a powerful tool for new target identification, drug discovery, and mechanism study; | |||
L7700 | Neural Regeneration Compound Library | 529 compounds | |
A unique collection of 149 neuroregeneration related compounds for high throughput and high content screening; |