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Suciraslimab
(Synonyms: SM03, SM 03) Copy Product Info
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Synonyms: SM03, SM 03
Catalog No. T9901A-522 Copy Product Info
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Suciraslimab (SM03) is a human IgG1 monoclonal antibody against the B-cell restriction antigen CD22 for the treatment of rheumatoid arthritis (RA) and other B-cell related diseases.
Suciraslimab
Cas No. 2415439-63-1
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $247 | - | In Stock | |
| 5 mg | $619 | - | In Stock | |
| 10 mg | $953 | - | In Stock | |
| 25 mg | $1,390 | - | In Stock | |
| 50 mg | $1,880 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:>95.0% (SDS-PAGE); 97.42% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Antibody Information
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| Description | Suciraslimab (SM03) is a human IgG1 monoclonal antibody against the B-cell restriction antigen CD22 for the treatment of rheumatoid arthritis (RA) and other B-cell related diseases. |
| In vivo | In 5xFAD Alzheimer's disease mouse models, intraperitoneal injection of Suciraslimab (10 mg/kg, once weekly for 4 weeks) significantly enhanced microglial metabolic activity and phagocytosis, reduced brain amyloid plaque burden, and upregulated neuroprotective gene expression[1]. |
| Synonyms | SM03, SM 03 |
| Reactivity | Human |
| Verified Activity | Immobilized Human CD22 Protein (His) at 2 μg/mL can bind Suciraslimab. The EC50 is 0.004412 μg/mL.  |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | Siglec-2/CD22 |
| Molecular Weight | 146.16 kDa |
| Cas No. | 2415439-63-1 |
| Isotype | Human IgG1-REM kappa |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: Suciraslimab in vivo | Suciraslimab molecular weight
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