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Anti-Carbonic Anhydrase 12 Antibody (7S411)
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Catalog No. TMAY-01033
Alias HsT18816, FLJ20151, CAXII, carbonic anhydrase XII, CA12
Anti-Carbonic Anhydrase 12 Antibody (7S411) is a Mouse antibody targeting Carbonic Anhydrase 12. Anti-Carbonic Anhydrase 12 Antibody (7S411) can be used in FCM.
Anti-Carbonic Anhydrase 12 Antibody (7S411)
Anti-Carbonic Anhydrase 12 Antibody (7S411)
😃Good
Catalog No. TMAY-01033Alias HsT18816, FLJ20151, CAXII, carbonic anhydrase XII, CA12
Anti-Carbonic Anhydrase 12 Antibody (7S411) is a Mouse antibody targeting Carbonic Anhydrase 12. Anti-Carbonic Anhydrase 12 Antibody (7S411) can be used in FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $198 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: FCM Reactivity: Human |
| Alias | HsT18816, FLJ20151, CAXII, carbonic anhydrase XII, CA12 |
| Ig Type | Mouse IgG1 |
| Clone | 7S411 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human CA12 expression on MCF-7 cells. Cells were stained with purified anti-Human CA12, then a FITC-conjugated second step antibody. The histogram were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | FCM |
| Recommended Dose | FCM: 1:25-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Carbonic Anhydrase XII (rh Carbonic Anhydrase XII; TMPY-00694; NP_001209.1; Met1-Gln291). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. CA12, also known as Car12 and carbonic anhydrase XII, is a type I membrane enzyme of an N-terminal extracellular catalytic domain, a membrane-spanning α-helix, and a small intracellular C-terminal domain. It is highly expressed in colon, kidney, prostate, intestine and activated lymphocytes and moderately expressed in pancreas, ovary, and testis. Overexpression of the CA12 is observed in certain human cancers and is used as a tumor marker. rmCA12 corresponds to the extracellular domain and has both carbonic anhydrase activity and esterase activity. |
| Conjucates | Unconjugated |
| Others Formats | FITC/PE |
| Antibody Types Available | 3 |
| Immunogen | Recombinant Protein: Human Carbonic Anhydrase XII protein (TMPY-00694) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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