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Anti-SETD7 Antibody (8B368)
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Catalog No. TMAY-01753
Alias SET9, SET7/9, SET7, SET domain containing (lysine methyltransferase) 7, KMT7
Anti-SETD7 Antibody (8B368) is a Mouse antibody targeting SETD7. Anti-SETD7 Antibody (8B368) can be used in WB.
Anti-SETD7 Antibody (8B368)
Anti-SETD7 Antibody (8B368)
😃Good
Catalog No. TMAY-01753Alias SET9, SET7/9, SET7, SET domain containing (lysine methyltransferase) 7, KMT7
Anti-SETD7 Antibody (8B368) is a Mouse antibody targeting SETD7. Anti-SETD7 Antibody (8B368) can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: WB Reactivity: Human |
| Alias | SET9, SET7/9, SET7, SET domain containing (lysine methyltransferase) 7, KMT7 |
| Ig Type | Mouse IgG1 |
| Clone | 8B368 |
| Reactivity | Human |
| Verified Activity | Anti-SETD7 mouse monoclonal antibody at 1:500 dilution. -Lane A: Hela Whole Cell Lysate. -Lane B: MCF7 Whole Cell Lysate. -Lane C: NIH3T3 Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Mouse IgG H&L (Dylight800) at 1/15000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:41 kDa. -Observed band size:53 kDa(We are unsure as to the identity of these extra bands.) |
| Application | WB |
| Recommended Dose | WB: 1:500-1:1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human SETD7 / SET7 / 9 (rh SETD7 / SET7 / 9; TMPY-01229; NP_085151.1; Asp2-Lys366). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Histone-lysine N-methyltransferase SETD7, also known as SET domain containing (lysine methyltransferase) 7, SET7/9, Histone H3-K4 methyltransferase SETD7, H3-K4-HMTase SETD7, and SETD7, is a member of the histone-lysine methyltransferase family and SET7 subfamily. SETD7 is widely expressed and expressed in pancreatic islets. SETD7 contains three MORN repeats and one SET domain. SETD7 plays a central role in the transcriptional activation of genes such as collagenase or insulin. As a protein lysine methyltransferase (PKMT), SETD7 also has methyltransferase activity toward non-histone proteins such as p53/TP53, TAF1, and possibly TAF7 by recognizing and binding in substrate proteins. The mono-methyltransferase activity of SETD7 is achieved by disrupting the formation at near-attack conformations for the dimethylation reaction. SETD7 is also a novel coactivator of NF-kappaB and plays a role in inflammation and diabetes. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human SETD7 / SET7 / 9 protein (TMPY-01229) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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