Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Catechol O-methyltransferase (COMT) is a magnesium-dependent enzyme that mediates the transfer of methyl groups from S-adenosyl methionine to the hydroxyl group on dopamine, thus converting it to 3-methoxytyramine. COMT exists in two forms within tissues: a soluble form (S-COMT) and a membrane-bound form (MB-COMT). Its primary function is to regulate the levels of epinephrine, norepinephrine, and dopamine in the brain [1].
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Description | Catechol O-methyltransferase (COMT) is a magnesium-dependent enzyme that mediates the transfer of methyl groups from S-adenosyl methionine to the hydroxyl group on dopamine, thus converting it to 3-methoxytyramine. COMT exists in two forms within tissues: a soluble form (S-COMT) and a membrane-bound form (MB-COMT). Its primary function is to regulate the levels of epinephrine, norepinephrine, and dopamine in the brain [1]. |
Molecular Weight | N/A |
CAS No. | 9012-25-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Catechol O-methyltransferase 9012-25-3 inhibitor inhibit