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Anti-Carbonic Anhydrase VB Antibody (5T426) (Synonyms: MGC39962, CA-VB, carbonic anhydrase VB, mitochondrial)

Catalog No. TMAY-02315 Copy Product Info
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Anti-Carbonic Anhydrase VB Antibody (5T426) is a Rabbit antibody targeting Carbonic Anhydrase VB. Anti-Carbonic Anhydrase VB Antibody (5T426) can be used in ELISA.

Anti-Carbonic Anhydrase VB Antibody (5T426)

Copy Product Info
🥰Excellent
Catalog No. TMAY-02315
Synonyms MGC39962, CA-VB, carbonic anhydrase VB, mitochondrial

Anti-Carbonic Anhydrase VB Antibody (5T426) is a Rabbit antibody targeting Carbonic Anhydrase VB. Anti-Carbonic Anhydrase VB Antibody (5T426) can be used in ELISA.

Anti-Carbonic Anhydrase VB Antibody
(5T426)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$2697-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Carbonic Anhydrase VB Antibody (5T426) is a Rabbit antibody targeting Carbonic Anhydrase VB. Anti-Carbonic Anhydrase VB Antibody (5T426) can be used in ELISA.
SynonymsMGC39962, CA-VB, carbonic anhydrase VB, mitochondrial
Ig Type
Rabbit IgG
Clone
5T426
Reactivity
Human
Specificity
Human Carbonic Anhydrase VB
No cross-reactivity in ELISA with
Human CA2
Human CA3
Human CA4
Human CA5A
Human CA8
Application
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human Carbonic Anhydrase VB / CA5B (rh Carbonic Anhydrase VB / CA5B; TMPY-02133; Q9Y2D0; Cys34-Pro 317).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundCarbonic anhydrase 5B, also known as carbonate dehydratase VB, carbonic anhydrase VB, CA-VB and CA5B, is amember of the alpha-carbonic anhydrase family. The strongest expression of CA5B / CA-VB is in heart, pancreas, kidney, placenta, lung, and skeletal muscle. It is not expressed in liver. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. CAs show extensive diversity in tissue distribution and in their subcellular localization. CA5B / CA-VB is localized in the mitochondria and shows the highest sequence similarity to the other mitochondrial CA5A / CA-VA. CA5B / CA-VB has a wider tissue distribution than CA5A / CA-VA, which is restricted to the liver. The differences in tissue distribution suggest that the two mitochondrial carbonic anhydrases evolved to assume different physiologic roles. CA5A / CA-VA is activated by histamine, L-adrenaline, L- and D-histidine, and L- and D-phenylalanine. It is inhibited by coumarins, sulfonamide derivatives such as acetazolamide and Foscarnet (phosphonoformate trisodium salt). CA5B / CA-VB is inhibited by coumarins, sulfonamide derivatives such as acetazolamide (AZA), saccharin and Foscarnet (phosphonoformate trisodium salt).
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human Carbonic Anhydrase VB / CA5B protein (TMPY-02133)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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