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Carnidazole (Synonyms: NSC-293873, NSC293873, NSC 293873, ME-108, ME108, ME 108)

Name: Carnidazole
Brand: TargetMol
SKU: T20535
Rating: 4.5 (1 reviews)

Catalog No. T20535 Copy Product Info

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Carnidazole (ME-108) shows antiprotozoal activity and can be used in studies about the treatment of Trichomonas infection.

Carnidazole

Copy Product Info

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Catalog No. T20535

Synonyms NSC-293873, NSC293873, NSC 293873, ME-108, ME108, ME 108

Carnidazole (ME-108) shows antiprotozoal activity and can be used in studies about the treatment of Trichomonas infection.

Cas No. 42116-76-7

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Pack Size	Price	USA Stock	Global Stock
5 mg	$29	6-8 weeks	6-8 weeks
10 mg	$45	6-8 weeks	6-8 weeks
25 mg	$77	6-8 weeks	6-8 weeks
50 mg	$115	6-8 weeks	6-8 weeks
100 mg	$172	6-8 weeks	6-8 weeks
200 mg	$259	6-8 weeks	6-8 weeks
1 mL x 10 mM (in DMSO)	$37	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Product Introduction

Carnidazole AI Summary

Carnidazole shows a moderate partition coefficient with a LogP of 0.9, indicating its ability to potentially cross cell membranes and suggesting lipophilicity. It exhibits an excretion profile with amounts excreted in urine ranging from 6.5% to 23.1% over different time intervals and a gradual increase in biliary excretion in rats over time, suggesting a hepatic elimination pathway. It has a capacity factor (log k') of 0.465, indicating its behavior in chromatography. Additionally, Carnidazole demonstrates antiviral activity against SARS-CoV-2, with an IC50 value greater than 20,000 nM, indicating moderate potency in inhibiting virus-induced cytotoxicity in VERO-6 cells..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Carnidazole (ME-108) shows antiprotozoal activity and can be used in studies about the treatment of Trichomonas infection.
Synonyms	NSC-293873, NSC293873, NSC 293873, ME-108, ME108, ME 108

Chemical Properties

Molecular Weight	244.27
Formula	C₈H₁₂N₄O₃S
Cas No.	42116-76-7
Smiles	C(CNC(OC)=S)N1C(N(=O)=O)=CN=C1C
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 22.5 mg/mL (92.11 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.0938 mL	20.4692 mL	40.9383 mL	204.6915 mL
5 mM	0.8188 mL	4.0938 mL	8.1877 mL	40.9383 mL
10 mM	0.4094 mL	2.0469 mL	4.0938 mL	20.4692 mL
20 mM	0.2047 mL	1.0235 mL	2.0469 mL	10.2346 mL
50 mM	0.0819 mL	0.4094 mL	0.8188 mL	4.0938 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc