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C3361
Catalog No. T213100 Copy Product Info
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C3361 is a moderately selective inhibitor of the hexose transporter 1 from Plasmodium falciparum (PfHT1) and Plasmodium berghei (PbHT1), with Ki values of 8.6 μM and 9.4 μM, respectively. It also inhibits TgGT1 with Ki values of 8.6 μM and 82 μM. C3361 can inhibit the liver stage of Plasmodium berghei (IC50 = 15 μM) and block the development of ookinetes. Additionally, C3361 impedes the growth of blood-stage parasites and can be utilized in infection-related research, such as studies on malaria.
C3361
Copy Product Info🥰Excellent
Catalog No. T213100
C3361 is a moderately selective inhibitor of the hexose transporter 1 from Plasmodium falciparum (PfHT1) and Plasmodium berghei (PbHT1), with Ki values of 8.6 μM and 9.4 μM, respectively. It also inhibits TgGT1 with Ki values of 8.6 μM and 82 μM. C3361 can inhibit the liver stage of Plasmodium berghei (IC50 = 15 μM) and block the development of ookinetes. Additionally, C3361 impedes the growth of blood-stage parasites and can be utilized in infection-related research, such as studies on malaria.
C3361
Cas No. 91042-00-1
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | 10-14 weeks | 10-14 weeks | |
| 50 mg | Inquiry | 10-14 weeks | 10-14 weeks |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Storage & Solubility Information
| Description | C3361 is a moderately selective inhibitor of the hexose transporter 1 from Plasmodium falciparum (PfHT1) and Plasmodium berghei (PbHT1), with Ki values of 8.6 μM and 9.4 μM, respectively. It also inhibits TgGT1 with Ki values of 8.6 μM and 82 μM. C3361 can inhibit the liver stage of Plasmodium berghei (IC50 = 15 μM) and block the development of ookinetes. Additionally, C3361 impedes the growth of blood-stage parasites and can be utilized in infection-related research, such as studies on malaria. |
| In vitro | C3361 reduces the formation of motile zygotes by 75%. In liver stage schizonts in hepatoma cells infected by sporozoites, C3361 (1-100 μM, 68 h) inhibits maturation. It demonstrates growth inhibitory effects against P. berghei, with an IC50 value of 15 μM. Immunofluorescencein sporozoite-infected hepatoma cells shows a decreased area of liver schizonts at concentrations of 1, 10, 50, and 100 μM with 68-hour incubation. |
| In vivo | C3361 (2 mg/kg, intravenous injection, once daily) can reduce the parasitic burden in mice infected with blood cells expressing GFP. |
| Molecular Weight | 332.44 |
| Formula | C17H32O6 |
| Cas No. | 91042-00-1 |
| Smiles | O(CCCCCCCCCC=C)[C@H]1[C@H](O)[C@@H](CO)OC(O)[C@@H]1O |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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