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Anti-SETD7 Antibody (7Q70) is a Rabbit antibody targeting SETD7. Anti-SETD7 Antibody (7Q70) can be used in ELISA.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 μL | $270 | 7-10 days | 7-10 days |
| Description | Anti-SETD7 Antibody (7Q70) is a Rabbit antibody targeting SETD7. Anti-SETD7 Antibody (7Q70) can be used in ELISA. |
| Synonyms | SET9, SET7/9, SET7, SET domain containing (lysine methyltransferase) 7, KMT7 |
| Ig Type | Rabbit IgG |
| Clone | 7Q70 |
| Reactivity | Human |
| Specificity | Human SETD7 |
| Application | |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human SETD7 / SET7/9 (rh SETD7 / SET7/9; TMPY-01229; NP_085151.1; Asp2-Lys366). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Histone-lysine N-methyltransferase SETD7, also known as SET domain containing (lysine methyltransferase) 7, SET7/9, Histone H3-K4 methyltransferase SETD7, H3-K4-HMTase SETD7, and SETD7, is a member of the histone-lysine methyltransferase family and SET7 subfamily. SETD7 is widely expressed and expressed in pancreatic islets. SETD7 contains three MORN repeats and one SET domain. SETD7 plays a central role in the transcriptional activation of genes such as collagenase or insulin. As a protein lysine methyltransferase (PKMT), SETD7 also has methyltransferase activity toward non-histone proteins such as p53/TP53, TAF1, and possibly TAF7 by recognizing and binding in substrate proteins. The mono-methyltransferase activity of SETD7 is achieved by disrupting the formation at near-attack conformations for the dimethylation reaction. SETD7 is also a novel coactivator of NF-kappaB and plays a role in inflammation and diabetes. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human SETD7 / SET7/9 protein (TMPY-01229) |
| Antigen Species | Human |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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