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Linolelaidic acid

Name: Linolelaidic acid
Brand: TargetMol
SKU: TN7008
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: Linoelaidic acid, (9E,12E)-octadeca-9,12-dienoic acid) Copy Product Info

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Synonyms: Linoelaidic acid, (9E,12E)-octadeca-9,12-dienoic acid

Catalog No. TN7008 Copy Product Info

Purity: 99.91%

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Linolelaidic acid ((9E,12E)-octadeca-9,12-dienoic acid) is a major positive regulator of CTL activity, an essential nutrient for humans, with anti-inflammatory and anti-parasitic properties. It improves metabolic adaptability, prevents fatigue, and stimulates memory-like phenotypes with exceptional effects. It induces apoptosis and can be used in infection studies.

Cas No. 506-21-8

Pack Size	Price	USA Stock	Global Stock
10 mg	$31	-	In Stock
25 mg	$50	-	In Stock
50 mg	$70	-	In Stock
100 mg	$113	-	In Stock
1 mL x 10 mM (in DMSO)	$29	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.91%

Color:White

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COA GC HNMR

Product Introduction

Bioactivity

Description	Linolelaidic acid ((9E,12E)-octadeca-9,12-dienoic acid) is a major positive regulator of CTL activity, an essential nutrient for humans, with anti-inflammatory and anti-parasitic properties. It improves metabolic adaptability, prevents fatigue, and stimulates memory-like phenotypes with exceptional effects. It induces apoptosis and can be used in infection studies.
In vitro	Linolelaidic acid (20 μM) increased the mRNA and protein expression levels of PCNA, CDK2 and Cyclin E in human umbilical vein smooth muscle cells (HUVSMC). The proliferation effect of Linolelaidic acid on HUVSMC was stronger than that of oleic acid. [1] Linolelaidic acid stimulated the proliferation of MOLT-4 T lymphocytic leukemia cells at concentrations of 100 and 200 μM, but inhibited cell growth at concentrations of 400 μM. [2]
In vivo	Linolelaidic acid (10 mg/kg, orally, once daily for 4 days) demonstrated antiparasite activity in a mouse model of malaria C57BL/6 induced by P. berghei (ANKA) strain. [3]
Synonyms	Linoelaidic acid, (9E,12E)-octadeca-9,12-dienoic acid

Chemical Properties

Molecular Weight	280.45
Formula	C₁₈H₃₂O₂
Cas No.	506-21-8
Smiles	C(C/C=C/C/C=C/CCCCC)CCCCCC(O)=O
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

Store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 250 mg/mL (891.42 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+90% Saline: 10 mg/mL (35.66 mM), Suspension.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.5657 mL	17.8285 mL	35.6570 mL	178.2849 mL
5 mM	0.7131 mL	3.5657 mL	7.1314 mL	35.6570 mL
10 mM	0.3566 mL	1.7828 mL	3.5657 mL	17.8285 mL
20 mM	0.1783 mL	0.8914 mL	1.7828 mL	8.9142 mL
50 mM	0.0713 mL	0.3566 mL	0.7131 mL	3.5657 mL
100 mM	0.0357 mL	0.1783 mL	0.3566 mL	1.7828 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Linolelaidic acid

Related Tags: Linolelaidic acid chemical structure | Linolelaidic acid in vivo | Linolelaidic acid in vitro | Linolelaidic acid formula | Linolelaidic acid molecular weight