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Linolelaidic acid

Name: Linolelaidic acid
Brand: TargetMol
SKU: TN7008
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN7008Cas No. 506-21-8

Alias Linoelaidic acid, (9E,12E)-octadeca-9,12-dienoic acid

Linolelaidic acid ((9E,12E)-octadeca-9,12-dienoic acid) is a major positive regulator of CTL activity, an essential nutrient for humans, with anti-inflammatory and anti-parasitic properties. It improves metabolic adaptability, prevents fatigue, and stimulates memory-like phenotypes with exceptional effects. It induces apoptosis and can be used in infection studies.

Linolelaidic acid

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Purity: 99.91%

Catalog No. TN7008Alias Linoelaidic acid, (9E,12E)-octadeca-9,12-dienoic acidCas No. 506-21-8

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
50 mg	$49	-	In Stock
1 mL x 10 mM (in DMSO)	$29	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.91%

Color:White

Resource Download

COA HNMR GC

Product Introduction

Bioactivity

Description	Linolelaidic acid ((9E,12E)-octadeca-9,12-dienoic acid) is a major positive regulator of CTL activity, an essential nutrient for humans, with anti-inflammatory and anti-parasitic properties. It improves metabolic adaptability, prevents fatigue, and stimulates memory-like phenotypes with exceptional effects. It induces apoptosis and can be used in infection studies.
In vitro	Linolelaidic acid (20 μM) increased the mRNA and protein expression levels of PCNA, CDK2 and Cyclin E in human umbilical vein smooth muscle cells (HUVSMC). The proliferation effect of Linolelaidic acid on HUVSMC was stronger than that of oleic acid. [1] Linolelaidic acid stimulated the proliferation of MOLT-4 T lymphocytic leukemia cells at concentrations of 100 and 200 μM, but inhibited cell growth at concentrations of 400 μM. [2]
In vivo	Linolelaidic acid (10 mg/kg, orally, once daily for 4 days) demonstrated antiparasite activity in a mouse model of malaria C57BL/6 induced by P. berghei (ANKA) strain. [3]
Synonyms	Linoelaidic acid, (9E,12E)-octadeca-9,12-dienoic acid

Chemical Properties

Molecular Weight	280.45
Formula	C₁₈H₃₂O₂
Cas No.	506-21-8
Smiles	C(C/C=C/C/C=C/CCCCC)CCCCCC(O)=O
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

store at low temperature | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (356.57 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.5657 mL	17.8285 mL	35.6570 mL	178.2849 mL
5 mM	0.7131 mL	3.5657 mL	7.1314 mL	35.6570 mL
10 mM	0.3566 mL	1.7828 mL	3.5657 mL	17.8285 mL
20 mM	0.1783 mL	0.8914 mL	1.7828 mL	8.9142 mL
50 mM	0.0713 mL	0.3566 mL	0.7131 mL	3.5657 mL
100 mM	0.0357 mL	0.1783 mL	0.3566 mL	1.7828 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc