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Linolelaidic acid

Name: Linolelaidic acid
Brand: TargetMol
SKU: TN7008
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. TN7008Cas No. 506-21-8

Alias Linoelaidic acid, (9E,12E)-octadeca-9,12-dienoic acid

Linolelaidic acid ((9E,12E)-octadeca-9,12-dienoic acid) is a major positive regulator of CTL activity, an essential nutrient for humans, with anti-inflammatory and anti-parasitic properties. It improves metabolic adaptability, prevents fatigue, and stimulates memory-like phenotypes with exceptional effects. It induces apoptosis and can be used in infection studies.

Linolelaidic acid

🥰Excellent

Purity: 99.91%

Catalog No. TN7008Alias Linoelaidic acid, (9E,12E)-octadeca-9,12-dienoic acidCas No. 506-21-8

Pack Size	Price	Availability	Quantity
50 mg	$49	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock

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Purity:99.91%

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Product Introduction

Bioactivity

Description	Linolelaidic acid ((9E,12E)-octadeca-9,12-dienoic acid) is a major positive regulator of CTL activity, an essential nutrient for humans, with anti-inflammatory and anti-parasitic properties. It improves metabolic adaptability, prevents fatigue, and stimulates memory-like phenotypes with exceptional effects. It induces apoptosis and can be used in infection studies.
In vitro	Linolelaidic acid (20 μM) increased the mRNA and protein expression levels of PCNA, CDK2 and Cyclin E in human umbilical vein smooth muscle cells (HUVSMC). The proliferation effect of Linolelaidic acid on HUVSMC was stronger than that of oleic acid. [1] Linolelaidic acid stimulated the proliferation of MOLT-4 T lymphocytic leukemia cells at concentrations of 100 and 200 μM, but inhibited cell growth at concentrations of 400 μM. [2]
In vivo	Linolelaidic acid (10 mg/kg, orally, once daily for 4 days) demonstrated antiparasite activity in a mouse model of malaria C57BL/6 induced by P. berghei (ANKA) strain. [3]
Synonyms	Linoelaidic acid, (9E,12E)-octadeca-9,12-dienoic acid

Chemical Properties

Molecular Weight	280.45
Formula	C₁₈H₃₂O₂
Cas No.	506-21-8
Smiles	C(C/C=C/C/C=C/CCCCC)CCCCCC(O)=O
Relative Density.	1.31g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (356.57 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.5657 mL	17.8285 mL	35.6570 mL	178.2849 mL
5 mM	0.7131 mL	3.5657 mL	7.1314 mL	35.6570 mL
10 mM	0.3566 mL	1.7828 mL	3.5657 mL	17.8285 mL
20 mM	0.1783 mL	0.8914 mL	1.7828 mL	8.9142 mL
50 mM	0.0713 mL	0.3566 mL	0.7131 mL	3.5657 mL
100 mM	0.0357 mL	0.1783 mL	0.3566 mL	1.7828 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc