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Bithionol sulfoxide

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Catalog No. T10551Cas No. 844-26-8
Alias Bithionoloxide, 6,6'-SULFINYLBIS(2,4-DICHLOROPHENOL), 2,2'-Sulfinyl-bis(4,6-dichlorophenol)

Bithionol sulfoxide (Bithionoloxide) is a compound with inhibitory effects on parasites, suppressing the activity of Schistosoma japonicum and Fasciola hepatica.

Bithionol sulfoxide

Bithionol sulfoxide

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Purity: 98.76%
Catalog No. T10551Alias Bithionoloxide, 6,6'-SULFINYLBIS(2,4-DICHLOROPHENOL), 2,2'-Sulfinyl-bis(4,6-dichlorophenol)Cas No. 844-26-8
Bithionol sulfoxide (Bithionoloxide) is a compound with inhibitory effects on parasites, suppressing the activity of Schistosoma japonicum and Fasciola hepatica.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 mg$34In StockIn Stock
100 mg$48In StockIn Stock
1 mL x 10 mM (in DMSO)$35In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:98.76%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
Bithionol sulfoxide (Bithionoloxide) is a compound with inhibitory effects on parasites, suppressing the activity of Schistosoma japonicum and Fasciola hepatica.
In vitro
Bithionol sulfoxide (0.1-10 mg/mL, 72 hours) showed toxicity to Neoparamoeba parasites in seawater. [1]
In vivo
Bithionol sulfoxide significantly inhibited C.S. administration The oviposition of a worm.
Bithionol sulfoxide showed a slight insecticidal effect at high doses of 100 mg/kg. [2]
Bithionol sulfoxide is mutagenic against Salmonella typhimurium strains TA98 and TA100. [3]
SynonymsBithionoloxide, 6,6'-SULFINYLBIS(2,4-DICHLOROPHENOL), 2,2'-Sulfinyl-bis(4,6-dichlorophenol)
Chemical Properties
Molecular Weight372.05
FormulaC12H6Cl4O3S
Cas No.844-26-8
SmilesO=S(C=1C=C(Cl)C=C(Cl)C1O)C=2C=C(Cl)C=C(Cl)C2O
Relative Density.1.86 g/cm3
Storage & Solubility Information
Storagestore at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 200 mg/mL (537.56 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 5 mg/mL (13.44 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.6878 mL13.4391 mL26.8781 mL134.3905 mL
5 mM0.5376 mL2.6878 mL5.3756 mL26.8781 mL
10 mM0.2688 mL1.3439 mL2.6878 mL13.4391 mL
20 mM0.1344 mL0.6720 mL1.3439 mL6.7195 mL
50 mM0.0538 mL0.2688 mL0.5376 mL2.6878 mL
100 mM0.0269 mL0.1344 mL0.2688 mL1.3439 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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