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Bithionol sulfoxide

🥰Excellent
Catalog No. T10551Cas No. 844-26-8
Alias Bithionoloxide, 6,6'-SULFINYLBIS(2,4-DICHLOROPHENOL), 2,2'-Sulfinyl-bis(4,6-dichlorophenol)

Bithionol sulfoxide (Bithionoloxide) is a compound with inhibitory effects on parasites, suppressing the activity of Schistosoma japonicum and Fasciola hepatica.

Bithionol sulfoxide

Bithionol sulfoxide

🥰Excellent
Purity: 98.76%
Catalog No. T10551Alias Bithionoloxide, 6,6'-SULFINYLBIS(2,4-DICHLOROPHENOL), 2,2'-Sulfinyl-bis(4,6-dichlorophenol)Cas No. 844-26-8
Bithionol sulfoxide (Bithionoloxide) is a compound with inhibitory effects on parasites, suppressing the activity of Schistosoma japonicum and Fasciola hepatica.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 mg$34In StockIn Stock
100 mg$48In StockIn Stock
1 mL x 10 mM (in DMSO)$35In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:98.76%
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Product Introduction

Bioactivity
Description
Bithionol sulfoxide (Bithionoloxide) is a compound with inhibitory effects on parasites, suppressing the activity of Schistosoma japonicum and Fasciola hepatica.
In vitro
Bithionol sulfoxide (0.1-10 mg/mL, 72 hours) showed toxicity to Neoparamoeba parasites in seawater. [1]
In vivo
Bithionol sulfoxide significantly inhibited C.S. administration The oviposition of a worm.
Bithionol sulfoxide showed a slight insecticidal effect at high doses of 100 mg/kg. [2]
Bithionol sulfoxide is mutagenic against Salmonella typhimurium strains TA98 and TA100. [3]
SynonymsBithionoloxide, 6,6'-SULFINYLBIS(2,4-DICHLOROPHENOL), 2,2'-Sulfinyl-bis(4,6-dichlorophenol)
Chemical Properties
Molecular Weight372.05
FormulaC12H6Cl4O3S
Cas No.844-26-8
SmilesO=S(C=1C=C(Cl)C=C(Cl)C1O)C=2C=C(Cl)C=C(Cl)C2O
Relative Density.1.86 g/cm3
Storage & Solubility Information
Storagestore at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 200 mg/mL (537.56 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 5 mg/mL (13.44 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.6878 mL13.4391 mL26.8781 mL134.3905 mL
5 mM0.5376 mL2.6878 mL5.3756 mL26.8781 mL
10 mM0.2688 mL1.3439 mL2.6878 mL13.4391 mL
20 mM0.1344 mL0.6720 mL1.3439 mL6.7195 mL
50 mM0.0538 mL0.2688 mL0.5376 mL2.6878 mL
100 mM0.0269 mL0.1344 mL0.2688 mL1.3439 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Bithionol sulfoxide
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