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Anti-Carbonic Anhydrase 14 Antibody (2I400)
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Catalog No. TMAY-00853
Alias CAXiV, carbonic anhydrase XIV, CA14
Anti-Carbonic Anhydrase 14 Antibody (2I400) is a Rabbit antibody targeting Carbonic Anhydrase 14. Anti-Carbonic Anhydrase 14 Antibody (2I400) can be used in ELISA.
Anti-Carbonic Anhydrase 14 Antibody (2I400)
Anti-Carbonic Anhydrase 14 Antibody (2I400)
😃Good
Catalog No. TMAY-00853Alias CAXiV, carbonic anhydrase XIV, CA14
Anti-Carbonic Anhydrase 14 Antibody (2I400) is a Rabbit antibody targeting Carbonic Anhydrase 14. Anti-Carbonic Anhydrase 14 Antibody (2I400) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $268 | 7-10 days |
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Product Introduction
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Antigen Details
Chemical Properties
| Description | Anti-Carbonic Anhydrase 14 Antibody (2I400) is a Rabbit antibody targeting Carbonic Anhydrase 14. Anti-Carbonic Anhydrase 14 Antibody (2I400) can be used in ELISA. |
| Alias | CAXiV, carbonic anhydrase XIV, CA14 |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 2I400 |
| Reactivity | Human |
| Verified Activity | Anti-CA14 rabbit monoclonal antibody at 1:500 dilution. -Lane A: Jurkat Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:38 kDa. -Observed band size:34 kDa |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human CA14 / Car14 extracellular domain (rh CA14; TMPY-00967; NP_036245.1; Met 1-Met 290). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons, a reversible reaction that takes part in maintaining acid-base balance in blood and other tissues. The carbonic anhydrasekl (CA) family consists of at least 11 enzymatically active members and a few inactive homologous proteins. CAXIV is a member of CA family that showed an overall similarity of 29–46% to other active CA isozymes. The highest percentage similarity was with a transmembrane CA isoform, CAXII. The CAXIV was found high concentrations in human heart, brain, liver, and skeletal muscle but lower in the colon, small intestine, urinary bladder, and kidney. No CAXIV mRNA was seen in the salivary gland and pancreas. CAXIV is a likely candidate for the extracellular CA postulated to have an important role in modulating excitatory synaptic transmission in brain. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human CA14 protein (TMPY-00967) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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