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Anti-RhoA Antibody (4F916) is a Mouse antibody targeting RhoA. Anti-RhoA Antibody (4F916) can be used in WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $222 | 7-10 days | |
100 μL | $372 | 7-10 days |
Description | Anti-RhoA Antibody (4F916) is a Mouse antibody targeting RhoA. Anti-RhoA Antibody (4F916) can be used in WB. |
Alias | RHOH12, RHO12, ras homolog family member A, ARHA, ARH12 |
Ig Type | IgG1,Κ |
Clone | 4F916 |
Reactivity | Human,Mouse,Rat |
Verified Activity | 25 μg total protein per Lane of various lysates probed with RHOA monoclonal antibody, unconjugated (TMAB-01616) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at RT for 60 min. |
Application | WB |
Recommended Dose | WB: 1:500-2000 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Subcellular Localization | Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytoskeleton. Cleavage furrow. Cytoplasm, cell cortex. Midbody. Note=Localized to cell-cell contacts in calcium-treated keratinocytes. Translocates to the equatorial region before furrow formation in a ECT2-dependent manner. Localizes to the equatorial cell cortex (at the site of the presumptive furrow) in early anaphase in a activated form and in a myosin- and actin-independent manner. |
Construction | Hybridoma Monoclonal Antibody |
Purification | Protein G purified |
Appearance | Liquid |
Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Research Background | This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
Immunogen | Recombinant Protein: human RhoA. |
Antigen Species | Human |
Gene ID | |
Uniprot ID | |
Biology Area | Ras Family,Actin Assembly,Ras family |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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