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Anti-RhoA Antibody (4F916)

😃Good
Catalog No. TMAB-01616
Alias RHOH12, RHO12, ras homolog family member A, ARHA, ARH12

Anti-RhoA Antibody (4F916) is a Mouse antibody targeting RhoA. Anti-RhoA Antibody (4F916) can be used in WB.

Anti-RhoA Antibody (4F916)

Anti-RhoA Antibody (4F916)

😃Good
Catalog No. TMAB-01616Alias RHOH12, RHO12, ras homolog family member A, ARHA, ARH12
Anti-RhoA Antibody (4F916) is a Mouse antibody targeting RhoA. Anti-RhoA Antibody (4F916) can be used in WB.
Pack SizePriceAvailabilityQuantity
50 μL$2227-10 days
100 μL$3727-10 days
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Product Introduction

Bioactivity
Description
Anti-RhoA Antibody (4F916) is a Mouse antibody targeting RhoA. Anti-RhoA Antibody (4F916) can be used in WB.
AliasRHOH12, RHO12, ras homolog family member A, ARHA, ARH12
Ig Type
IgG1,Κ
Clone
4F916
Reactivity
Human,Mouse,Rat
Verified Activity
25 μg total protein per Lane of various lysates probed with RHOA monoclonal antibody, unconjugated (TMAB-01616) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at RT for 60 min.
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular LocalizationCell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytoskeleton. Cleavage furrow. Cytoplasm, cell cortex. Midbody. Note=Localized to cell-cell contacts in calcium-treated keratinocytes. Translocates to the equatorial region before furrow formation in a ECT2-dependent manner. Localizes to the equatorial cell cortex (at the site of the presumptive furrow) in early anaphase in a activated form and in a myosin- and actin-independent manner.
ConstructionHybridoma Monoclonal Antibody
PurificationProtein G purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Research BackgroundThis gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Antigen Details
Immunogen
Recombinant Protein: human RhoA.
Antigen Species
Human
Gene ID
Uniprot ID
Biology Area
Ras Family,Actin Assembly,Ras family
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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