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Anti-Carbonic Anhydrase 14 Antibody (4J346) is a Rabbit antibody targeting Carbonic Anhydrase 14. Anti-Carbonic Anhydrase 14 Antibody (4J346) can be used in ELISA(Cap).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
20 μL | $93 | 7-10 days | |
100 μL | $269 | 7-10 days |
Description | Anti-Carbonic Anhydrase 14 Antibody (4J346) is a Rabbit antibody targeting Carbonic Anhydrase 14. Anti-Carbonic Anhydrase 14 Antibody (4J346) can be used in ELISA(Cap). |
Alias | CAXiV, carbonic anhydrase XIV, CA14 |
Ig Type | Monoclonal Rabbit IgG |
Clone | 4J346 |
Reactivity | Human |
Application | ELISA(Cap) |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human Carbonic Anhydrase XIV (rh Carbonic Anhydrase XIV; TMPY-00967; NP_036245.1; Met1-Met290). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons, a reversible reaction that takes part in maintaining acid-base balance in blood and other tissues. The carbonic anhydrasekl (CA) family consists of at least 11 enzymatically active members and a few inactive homologous proteins. CAXIV is a member of CA family that showed an overall similarity of 29–46% to other active CA isozymes. The highest percentage similarity was with a transmembrane CA isoform, CAXII. The CAXIV was found high concentrations in human heart, brain, liver, and skeletal muscle but lower in the colon, small intestine, urinary bladder, and kidney. No CAXIV mRNA was seen in the salivary gland and pancreas. CAXIV is a likely candidate for the extracellular CA postulated to have an important role in modulating excitatory synaptic transmission in brain. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human Carbonic Anhydrase XIV Protein (TMPY-00967) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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