tp-α

L 888607 Racemate is a selective antagonist of the prostaglandin D2 receptor subtype 1 (DP1) with Ki values of 132 nM and 17 nM for DP1 and the thromboxane A2 receptor (TP), respectively.

Eravacycline (TP-434) is a potent and broad-spectrum antibacterial agent.

Eravacycline dihydrochloride (TP-434-046) is a potent and broad-spectrum antibacterial agent against six E. coli (MICs: 0.125-0.25 mg/L).

Eravacycline HCl (TP-434 HCl) is potent antibiotic with broad-spectrum antibacterial activity.

TP-16 is a novel potent and selective EP4 antagonist that blocks the function of IMCs and enhances cytotoxic T cell-mediated tumor elimination in vivo.

Bardoxolone Methyl (TP-155) is a synthetic triterpenoid that acts as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway with potential anti-tumor and anti-inflammatory activities.

EFdA-TP 3TEA is the salt form of EFdA-TP.EFdA-TP 3TEA is a nucleoside analog that is a novel, potent, and selective nucleoside reverse transcriptase (RT) inhibitor that inhibits HIV-1 reverse transcriptase by multiple mechanisms, thereby increasing its drug resistance.

TP-353 (EOS-61973) is a CDK7 inhibitor.

TP808 is a highly versatile intermediate for the construction of a wide range of tetracycline antibiotics.

TP-2857 (TAP2857) is a potent antimicrobial agent.

CDDO-EA (CDDO ethyl amide) is an activator of the Nrf2/antioxidant response element.

TGFβRI-IN-2 is a selective, potent and orally active inhibitor of (Activin-Like Kinase 5) ALK 5(pIC50 and pEC50 values of 7.6 and 6.63, respectively).

TP-004 is a potent, reversible inhibitor of methionine aminopeptidase 2 (MetAP2) with an IC50 of 6 nM.

TP-10 is a selective inhibitor of PDE10A against other PDEs with IC50 of 0.8 nM.

TP-472 is a selective inhibitor of BRD9 (Kd: 33 nM).

TP3011 is a potent topoisomerase I inhibitor equipotent as SN38 and is an active metabolite of CH-0793076.

Atiratecan (TP300) is a prodrug of camptothecin analog CH0793076. Atiratecan shows antitumor activity against both breast cancer resistance protein (BCRP)-positive and -negative xenografts in mouse xenograft models[1]. Atiratecan does not inhibit acetylch

CH-0793076, a hexacyclic camptothecin analog, is an active drug and major metabolite of TP300. CH-0793076 is efficacious against cells expressing BCRP (breast cancer resistance protein). CH-0793076 inhibits DNA topoisomerase I (IC50: 2.3 μM).

Laropiprant (MK-0524) is a potent and selective antagonist of prostaglandin D2 (PGD2) receptor (DP) such as and DP/DP1 receptor(Ki = 0.57 nM) and TP Receptor(Ki = 2.95 nM).

L 888607 is an effective and selective CRTH2 agonist (Ki: 0.8 nM).

Dubermatinib (TP0903) is a potent and selective Axl kinase inhibitor.

Clofarabine-5'-triphosphate is a metabolite of Clofarabine, produced via phosphorylation by deoxycytidine kinase (dCK). It exhibits cytotoxicity in cancer cells by inhibiting DNA synthesis and DNA repair.

TP prodrug (compound 15) is an effective and orally active anti-SARS-CoV-2 agent. The 13-TP prodrug exhibits cytotoxic properties and can reduce the expression of the SARS-CoV-2 N protein. Additionally, the 13-TP prodrug demonstrates antiviral activity.

Selank is a synthetic analog of tuftsin.