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HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Monomer Protein, Human, MHC (E. coli, His & Avi), Biotinylated
(Synonyms: TRP53, TP53, P53, MHC, LFS1, HLA-A, FLJ92943, BCC7, Antigen NY-CO-13) Copy Product InfoSynonyms: TRP53, TP53, P53, MHC, LFS1, HLA-A, FLJ92943, BCC7, Antigen NY-CO-13
Catalog No. TMPK-01802 Copy Product Info
HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Monomer Protein, Human, MHC (E. coli, His & Avi), Biotinylated is expressed in E. coli. The accession number is A0A140T913(HLA-A*02:01)&P61769(B2M)&HMTEVVRHC.
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $96 | 7-10 days | 7-10 days | |
| 10 µg | $147 | 7-10 days | 7-10 days | |
| 20 µg | $228 | 7-10 days | 7-10 days | |
| 50 µg | $419 | 7-10 days | 7-10 days | |
| 100 µg | $665 | 7-10 days | 7-10 days | |
| 200 µg | $1,050 | 7-10 days | 7-10 days | |
| 500 µg | $1,960 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Immobilized Biotinylated Human HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Monomer, His Tag at 1 μg/ml (100 μl/well) on the streptavidin precoated plate (5 μg/ml). Dose response curve for Anti-B2M Antibody, mFc Tag with the EC50 of 11.5 ng/ml determined by ELISA. |
| Description | HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Monomer Protein, Human, MHC (E. coli, His & Avi), Biotinylated is expressed in E. coli. The accession number is A0A140T913(HLA-A*02:01)&P61769(B2M)&HMTEVVRHC. |
| Species | Human |
| Expression System | E. coli |
| Tag | C-His-Avi |
| Accession Number | A0A140T913(HLA-A*02:01)&P61769(B2M)&HMTEVVRHC |
| Construction | Gly25-Thr305 (HLA-A*02:01), Ile21-Met119 (B2M) and HMTEVVRHC peptide |
| Protein Purity | > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC |
| Endotoxin | < 1 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from 0.22 μm filtered solution in 20 mM Tris, 200 mM NaCl (pH 8.0). Normally 8% mannitol is added as protectant before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | TRP53, TP53, P53, MHC, LFS1, HLA-A, FLJ92943, BCC7, Antigen NY-CO-13 |
| Research Background | p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell proliferation and tumor progression. Depending on the p53 mutation, it has been shown to form aggregates leading to negative gain of function of the protein.p53 mutant associated aggregation has been observed in several cancer tissues and has been shown to promote tumor growth. |
| Molecular Weight | 35.6 kDa (HLA-A*02:01) and 11.9 kDa (B2M) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Monomer Protein, Human, MHC (E. coli, His & Avi), Biotinylated chemical structure | HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Monomer Protein, Human, MHC (E. coli, His & Avi), Biotinylated molecular weight
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