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Anti-ATP2C1 Monoclonal Antibody (3A850)
(Synonyms: SPCA1, PMR1, HHD, BCPM) Copy Product Info
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Synonyms: SPCA1, PMR1, HHD, BCPM
Catalog No. TMAT-0124 Copy Product Info
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Anti-ATP2C1 Monoclonal Antibody (3A850) is a Mouse antibody targeting ATP2C1. Anti-ATP2C1 Monoclonal Antibody (3A850) can be used in WB,IHC.
Anti-ATP2C1 Monoclonal Antibody
(3A850)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 µL | Inquiry | 7-10 days | 7-10 days | |
| 50 µL | Inquiry | 7-10 days | 7-10 days | |
| 100 µL | Inquiry | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-ATP2C1 Monoclonal Antibody (3A850) is a Mouse antibody targeting ATP2C1. Anti-ATP2C1 Monoclonal Antibody (3A850) can be used in WB,IHC. |
| Synonyms | SPCA1, PMR1, HHD, BCPM |
| Ig Type | IgG1 |
| Clone | 3A850 |
| Reactivity | Human,Monkey |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | Ascitic fluid containing 0.03% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | ATP2C1, also known as PMR1, it belongs to the family of P-type cation transport ATPases. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of the calcium. The human homologue, ATP2C1 (also designated SPLA in rat), also regulates the transport of calcium in the Golgi complex and is related to other P-type ATPases family members, such as the sarco(endo)plasmic calcium ATPase (SERCA) and the plasma membrane calcium ATPase (PCMA). ATP2C1 is a transmembrane protein that exists as two splice variants, which vary by 20 amino acids. Defects in ATP2C1 cause Hailey-Hailey disease, which is an autosomal dominant disorder that is characterized by blisters and erosions of the skin. These findings provide further evidence that PMR1 plays a key role in maintaining the integrity of the epidermis by controlling intracellular calcium signaling. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of ATP2C1 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | ATP2C1 |
| Gene ID | |
| Protein Name | Calcium-transporting ATPase type 2C member 1 |
| Uniprot ID |
| Molecular Weight | Theoretical: 100 kDa |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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