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Synonyms: PrPc, PrP33-35C, PrP27-30, PrP, PRNP, PRIP, p27-30, KURU, GSS, CJD, ASCR, AltPrP
Anti-CD230 Monoclonal Antibody
(8K377)

| Description | Anti-CD230 Monoclonal Antibody (8K377) is a Mouse antibody targeting CD230. Anti-CD230 Monoclonal Antibody (8K377) can be used in FCM. |
| Synonyms | PrPc, PrP33-35C, PrP27-30, PrP, PRNP, PRIP, p27-30, KURU, GSS, CJD, ASCR, AltPrP |
| Ig Type | IgG1 |
| Clone | 8K377 |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014] |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human CD230 (AA: 23-230) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | PRNP |
| Gene ID | |
| Protein Name | Major prion protein |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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