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Anti-CD230 Monoclonal Antibody (8K377)

(Synonyms: PrPc, PrP33-35C, PrP27-30, PrP, PRNP, PRIP, p27-30, KURU, GSS, CJD, ASCR, AltPrP) Copy Product Info
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Synonyms: PrPc, PrP33-35C, PrP27-30, PrP, PRNP, PRIP, p27-30, KURU, GSS, CJD, ASCR, AltPrP

Catalog No. TMAT-0335 Copy Product Info
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Anti-CD230 Monoclonal Antibody (8K377) is a Mouse antibody targeting CD230. Anti-CD230 Monoclonal Antibody (8K377) can be used in FCM.

Anti-CD230 Monoclonal Antibody
(8K377)

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Product Introduction

Bioactivity
Description
Anti-CD230 Monoclonal Antibody (8K377) is a Mouse antibody targeting CD230. Anti-CD230 Monoclonal Antibody (8K377) can be used in FCM.
SynonymsPrPc, PrP33-35C, PrP27-30, PrP, PRNP, PRIP, p27-30, KURU, GSS, CJD, ASCR, AltPrP
Ig Type
IgG1
Clone
8K377
Reactivity
Human
Application
Recommended Dose
FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/ml
Research BackgroundThe protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human CD230 (AA: 23-230) expressed in E. Coli.
Antigen Species
Human
Gene Name
PRNP
Gene ID
Protein Name
Major prion protein
Uniprot ID
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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