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Anti-CD27/TNFRSF7 Antibody (2A27)
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Catalog No. TMAY-00142
Alias Tp55, Tnfrsf7, S152, CD27 molecule
Anti-CD27/TNFRSF7 Antibody (2A27) is a Rabbit antibody targeting CD27/TNFRSF7. Anti-CD27/TNFRSF7 Antibody (2A27) can be used in FCM.
Anti-CD27/TNFRSF7 Antibody (2A27)
Anti-CD27/TNFRSF7 Antibody (2A27)
😃Good
Catalog No. TMAY-00142Alias Tp55, Tnfrsf7, S152, CD27 molecule
Anti-CD27/TNFRSF7 Antibody (2A27) is a Rabbit antibody targeting CD27/TNFRSF7. Anti-CD27/TNFRSF7 Antibody (2A27) can be used in FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $270 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CD27/TNFRSF7 Antibody (2A27) is a Rabbit antibody targeting CD27/TNFRSF7. Anti-CD27/TNFRSF7 Antibody (2A27) can be used in FCM. |
| Alias | Tp55, Tnfrsf7, S152, CD27 molecule |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 2A27 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human CD27 expression on human whole blood lymphocytes. Cells were stained with purified anti-Human CD27, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
| Application | FCM |
| Recommended Dose | FCM: 1:25-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD27 (rh CD27; NP_001233.1Met1-Ile192). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | CD27, also known as TNFRSF7, is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage, and exists as both a dimeric glycoprotein on the cell surface and as a soluble protein in serum. As a type I transmembrane glycoprotein of about 55 kDa existing as disulfide-linked homodimer, CD27 has been shown to play roles in lymphoid proliferation, differentiation, and apoptosis.It has an important role in the generation of T cell immunity and is an robust marker for normal memory B cells. It is a T and B cell co-stimulatory molecule, the activity of CD27 is governed by its TNF-like ligand CD70 on lymphocytes and dendritic cells. The CD27-CD70 interaction is required for Th1 generation responses to differentiation signals and long-term maintenance of T cell immunity, and meanwhile, plays a key role in regulating B-cell differentiation, activation and immunoglobulin synthesis.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: IHC AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Others Formats | APC/PerCP/FITC/PE |
| Antibody Types Available | 5 |
| Immunogen | Recombinant Human CD27 Protein |
| Antigen Species | Human |
| Biology Area | Cancer Drug Targets |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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