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Synonyms: TP73L, TP63,AIS, TP53L, TP53CP, SHFM4, RHS, p73L, p73H, p63, p53CP, p51, p40, OFC8, NBP, LMS, KET, EEC3, B(p51B), B(p51A)
Anti-TP63 Monoclonal Antibody
(6P145)

| Description | Anti-TP63 Monoclonal Antibody (6P145) is a Mouse antibody targeting TP63. Anti-TP63 Monoclonal Antibody (6P145) can be used in IHC,FCM. |
| Synonyms | TP73L, TP63,AIS, TP53L, TP53CP, SHFM4, RHS, p73L, p73H, p63, p53CP, p51, p40, OFC8, NBP, LMS, KET, EEC3, B(p51B), B(p51A) |
| Ig Type | IgG1 |
| Clone | 6P145 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an oligomerization domain. Alternative splicing of this gene and the use of alternative promoters results in multiple transcript variants encoding different isoforms that vary in their functional properties. These isoforms function during skin development and maintenance, adult stem/progenitor cell regulation, heart development and premature aging. Some isoforms have been found to protect the germline by eliminating oocytes or testicular germ cells that have suffered DNA damage. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human TP63 (AA: 5-17) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | TP63 |
| Gene ID | |
| Protein Name | Tumor protein 63 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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