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Anti-TP63 Monoclonal Antibody (6P145)

(Synonyms: TP73L, TP63,AIS, TP53L, TP53CP, SHFM4, RHS, p73L, p73H, p63, p53CP, p51, p40, OFC8, NBP, LMS, KET, EEC3, B(p51B), B(p51A)) Copy Product Info
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Synonyms: TP73L, TP63,AIS, TP53L, TP53CP, SHFM4, RHS, p73L, p73H, p63, p53CP, p51, p40, OFC8, NBP, LMS, KET, EEC3, B(p51B), B(p51A)

Catalog No. TMAT-1543 Copy Product Info
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Anti-TP63 Monoclonal Antibody (6P145) is a Mouse antibody targeting TP63. Anti-TP63 Monoclonal Antibody (6P145) can be used in IHC,FCM.

Anti-TP63 Monoclonal Antibody
(6P145)

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Product Introduction

Bioactivity
Description
Anti-TP63 Monoclonal Antibody (6P145) is a Mouse antibody targeting TP63. Anti-TP63 Monoclonal Antibody (6P145) can be used in IHC,FCM.
SynonymsTP73L, TP63,AIS, TP53L, TP53CP, SHFM4, RHS, p73L, p73H, p63, p53CP, p51, p40, OFC8, NBP, LMS, KET, EEC3, B(p51B), B(p51A)
Ig Type
IgG1
Clone
6P145
Reactivity
Human
Application
Recommended Dose
IHC: 1/200-1/1000; FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/mL
Research BackgroundThis gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an oligomerization domain. Alternative splicing of this gene and the use of alternative promoters results in multiple transcript variants encoding different isoforms that vary in their functional properties. These isoforms function during skin development and maintenance, adult stem/progenitor cell regulation, heart development and premature aging. Some isoforms have been found to protect the germline by eliminating oocytes or testicular germ cells that have suffered DNA damage. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human TP63 (AA: 5-17) expressed in E. Coli.
Antigen Species
Human
Gene Name
TP63
Gene ID
Protein Name
Tumor protein 63
Uniprot ID
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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