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Anti-MYLK Monoclonal Antibody (1O734)
(Synonyms: smMLCK, MYLK1, MSTP083, MMIHS, MLCK210, MLCK108, MLCK1, MLCK, KRP, AAT7) Copy Product Info
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Synonyms: smMLCK, MYLK1, MSTP083, MMIHS, MLCK210, MLCK108, MLCK1, MLCK, KRP, AAT7
Catalog No. TMAT-1344 Copy Product Info
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Anti-MYLK Monoclonal Antibody (1O734) is a Mouse antibody targeting MYLK. Anti-MYLK Monoclonal Antibody (1O734) can be used in WB,IHC,IF,FCM.
Anti-MYLK Monoclonal Antibody
(1O734)
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| Description | Anti-MYLK Monoclonal Antibody (1O734) is a Mouse antibody targeting MYLK. Anti-MYLK Monoclonal Antibody (1O734) can be used in WB,IHC,IF,FCM. |
| Synonyms | smMLCK, MYLK1, MSTP083, MMIHS, MLCK210, MLCK108, MLCK1, MLCK, KRP, AAT7 |
| Ig Type | IgG1 |
| Clone | 1O734 |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human MYLK (AA:1375-1524) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | MYLK |
| Gene ID | |
| Protein Name | Myosin light chain kinase, smooth muscle |
| Uniprot ID |
| Molecular Weight | Theoretical: 210 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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