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Synonyms: SERCA1, ATP2A
Anti-ATP2A1 Monoclonal Antibody
(3R886)

| Description | Anti-ATP2A1 Monoclonal Antibody (3R886) is a Mouse antibody targeting ATP2A1. Anti-ATP2A1 Monoclonal Antibody (3R886) can be used in WB,FCM. |
| Synonyms | SERCA1, ATP2A |
| Ig Type | IgG1 |
| Clone | 3R886 |
| Reactivity | Human,Mouse,Monkey |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in three transcript variants encoding different isoforms. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human ATP2A1 (AA: 487-631) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | ATP2A1 |
| Gene ID | |
| Protein Name | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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