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CGN peptide

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Catalog No. TP3256Cas No. 2421211-40-5

CGN peptide is a polypeptide composed of 13 D-amino acids, abbreviated as CGN peptide. It is the retro-inverso isomer of the L-peptide TGN (TGNYKALHPHNG), capable of targeting siRNA delivery to the blood-brain barrier (BBB). d(CGNHPHLAKYNGT) can be utilized in Alzheimer's disease (AD) research.

CGN peptide

CGN peptide

😃Good
Catalog No. TP3256Cas No. 2421211-40-5
CGN peptide is a polypeptide composed of 13 D-amino acids, abbreviated as CGN peptide. It is the retro-inverso isomer of the L-peptide TGN (TGNYKALHPHNG), capable of targeting siRNA delivery to the blood-brain barrier (BBB). d(CGNHPHLAKYNGT) can be utilized in Alzheimer's disease (AD) research.
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Product Introduction

Bioactivity
Description
CGN peptide is a polypeptide composed of 13 D-amino acids, abbreviated as CGN peptide. It is the retro-inverso isomer of the L-peptide TGN (TGNYKALHPHNG), capable of targeting siRNA delivery to the blood-brain barrier (BBB). d(CGNHPHLAKYNGT) can be utilized in Alzheimer's disease (AD) research.
Chemical Properties
Molecular Weight1411.55
FormulaC60H90N20O18S
Cas No.2421211-40-5
SmilesC([C@@H](CC1=CN=CN1)NC([C@H](NC(CNC([C@@H](CS)N)=O)=O)CC(N)=O)=O)(=O)N2[C@@H](C(N[C@H](CC3=CN=CN3)C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@H](CC4=CC=C(O)C=C4)C(N[C@@H](C(NCC(N[C@H]([C@H](C)O)C(O)=O)=O)=O)CC(N)=O)=O)=O)CCCCN)=O)C)=O)CC(C)C)=O)=O)CCC2
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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