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Thymosin β4 (Tβ4) is a thymic hormone with multiple and different intracellular and extracellular activities affecting wound healing, inflammation, fibrosis and tissue regeneration.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $78 | In Stock | In Stock | |
| 5 mg | $258 | In Stock | In Stock | |
| 10 mg | $361 | In Stock | In Stock | |
| 25 mg | $592 | In Stock | In Stock | |
| 50 mg | $849 | In Stock | In Stock | |
| 100 mg | $1,150 | In Stock | In Stock |
| Description | Thymosin β4 (Tβ4) is a thymic hormone with multiple and different intracellular and extracellular activities affecting wound healing, inflammation, fibrosis and tissue regeneration. |
| In vitro | Thymosin b4 can stimulate migration of cardiomyocytes and endothelial cells and promotes survival of cardiomyocytes. The LIM domain protein PINCH18 and ILK19, both of which are necessary for cell migration and survival, formed a complex with thymosin b4 that resulted in phosphorylation of the survival kinase Akt. |
| In vivo | Treatment of adult mice with thymosin b4 after coronary ligation resulted in increased phosphorylation of Akt in the heart, enhanced early myocyte survival and improved cardiac function. |
| Molecular Weight | 5023.56 |
| Formula | C214H354N56O80S |
| Cas No. | 1346423-89-9 |
| Smiles | CCC(C)C(C(=O)NC(CCC(=O)O)C(=O)NC(CCCCN)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CC(=O)O)C(=O)NC(CCCCN)C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(C(C)O)C(=O)NC(CCC(=O)O)C(=O)NC(C(C)O)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(CCCCN)C(=O)NC(CC(=O)N)C(=O)N2CCCC2C(=O)NC(CC(C)C)C(=O)N3CCCC3C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CCC(=O)O)C(=O)NC(C(C)O)C(=O)NC(C(C)CC)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(CCCCN)C(=O)NC(CCC(=O)N)C(=O)NC(C)C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(CO)C(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C(CCSC)NC(=O)C(CC(=O)O)NC(=O)C4CCCN4C(=O)C(CCCCN)NC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C.CC(=O)O |
| Relative Density. | no data available |
| Sequence | Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-xiIle-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-xiThr-Glu-xiThr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-xiThr-xiIle-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser-OH.CH3CO2H |
| Sequence Short | SDKPDMAEXEKFDKSKLKKXEXQEKNPLPSKEXXEQEKQAGES |
| Storage | keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||
| Solubility Information | H2O: 5 mM, Sonication is recommended. DMSO: Insoluble | |||||||||||||||
Solution Preparation Table | ||||||||||||||||
H2O
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Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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