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Anti-PTPRF Monoclonal Antibody (7U729)
(Synonyms: LAR, BNAH2) Copy Product Info
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Synonyms: LAR, BNAH2
Catalog No. TMAT-0796 Copy Product Info
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Anti-PTPRF Monoclonal Antibody (7U729) is a Mouse antibody targeting PTPRF. Anti-PTPRF Monoclonal Antibody (7U729) can be used in FCM.
Anti-PTPRF Monoclonal Antibody
(7U729)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-PTPRF Monoclonal Antibody (7U729) is a Mouse antibody targeting PTPRF. Anti-PTPRF Monoclonal Antibody (7U729) can be used in FCM. |
| Synonyms | LAR, BNAH2 |
| Ig Type | IgG1 |
| Clone | 7U729 |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains three Ig-like domains, and nine non-Ig like domains similar to that of neural-cell adhesion molecule. This PTP was shown to function in the regulation of epithelial cell-cell contacts at adherents junctions, as well as in the control of beta-catenin signaling. An increased expression level of this protein was found in the insulin-responsive tissue of obese, insulin-resistant individuals, and may contribute to the pathogenesis of insulin resistance. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human PTPRF (AA: extra 1104-1163) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | PTPRF |
| Gene ID | |
| Protein Name | Receptor-type tyrosine-protein phosphatase F |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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