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Anti-PTPN6 Monoclonal Antibody (3C781)
(Synonyms: SH-PTP1, SHP-1L, SHP-1, SHP1, PTP-1C, HPTP1C, HCPH, HCP) Copy Product Info
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Synonyms: SH-PTP1, SHP-1L, SHP-1, SHP1, PTP-1C, HPTP1C, HCPH, HCP
Catalog No. TMAT-0965 Copy Product Info
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Anti-PTPN6 Monoclonal Antibody (3C781) is a Mouse antibody targeting PTPN6. Anti-PTPN6 Monoclonal Antibody (3C781) can be used in IF,FCM.
Anti-PTPN6 Monoclonal Antibody
(3C781)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-PTPN6 Monoclonal Antibody (3C781) is a Mouse antibody targeting PTPN6. Anti-PTPN6 Monoclonal Antibody (3C781) can be used in IF,FCM. |
| Synonyms | SH-PTP1, SHP-1L, SHP-1, SHP1, PTP-1C, HPTP1C, HCPH, HCP |
| Ig Type | IgG1 |
| Clone | 3C781 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human PTPN6 (AA: 243-541) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | PTPN6 |
| Gene ID | |
| Protein Name | Tyrosine-protein phosphatase non-receptor type 6 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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