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Anti-CD45 Antibody (3Y331) is a Mouse antibody targeting CD45. Anti-CD45 Antibody (3Y331) can be used in FCM.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μg | $355 | 7-10 days |
Description | Anti-CD45 Antibody (3Y331) is a Mouse antibody targeting CD45. Anti-CD45 Antibody (3Y331) can be used in FCM. |
Alias | T200, PTPRC, LY5, L-CA, LCA, GP180, EC 3.1.3.48, CD45R, CD45, B220 |
Ig Type | Mouse IgG1, k |
Clone | 3Y331 |
Reactivity | Human |
Verified Activity | Blank control: Molt4. Primary Antibody (green line): Mouse Anti-CD45 antibody (TMAB-00372) Dilution: 1 μg/10^6 cells; Isotype Control Antibody (orange line): Mouse IgG. Secondary Antibody: Goat anti-mouse IgG-AF488 Dilution: 1 μg/test. Protocol The cells were incubated in 5% BSA to block non-specific protein-protein interactions for 30 min at room temperature. Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature. |
Application | FCM |
Recommended Dose | FCM: 1ug/Test |
Antibody Type | Monoclonal |
Host Species | Mouse |
Subcellular Localization | Membrane; Single-pass type I membrane protein. Membrane raft. Note=Colocalized with DPP4 in membrane rafts. |
Construction | Hybridoma Monoclonal Antibody |
Purification | Protein G purified |
Appearance | Liquid |
Formulation | 0.01M TBS (pH7.4). |
Research Background | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP. This gene is specifically expressed in hematopoietic cells. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling |
Immunogen | Recombinant Protein: human CD45 |
Antigen Species | Human |
Gene ID | |
Uniprot ID | |
Biology Area | Endothelial Cell Markers,CD,Regulatory T Cells,CD,Non-lineage,Microglia marker,Tyrosine Phosphatases,B Lymphocytic Lineage,NK Cell Lineage,T Lymphocytic Lineage,Dendritic Cell Lineage,Mast Cell Lineage,Monocytic Lineage,Neutrophil Lineage,Surface Molecules |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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