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Anti-CD45 Antibody (3Y331)

😃Good
Catalog No. TMAB-00372
Alias T200, PTPRC, LY5, L-CA, LCA, GP180, EC 3.1.3.48, CD45R, CD45, B220

Anti-CD45 Antibody (3Y331) is a Mouse antibody targeting CD45. Anti-CD45 Antibody (3Y331) can be used in FCM.

Anti-CD45 Antibody (3Y331)

Anti-CD45 Antibody (3Y331)

😃Good
Catalog No. TMAB-00372Alias T200, PTPRC, LY5, L-CA, LCA, GP180, EC 3.1.3.48, CD45R, CD45, B220
Anti-CD45 Antibody (3Y331) is a Mouse antibody targeting CD45. Anti-CD45 Antibody (3Y331) can be used in FCM.
Pack SizePriceAvailabilityQuantity
100 μg$3557-10 days
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Product Introduction

Bioactivity
Description
Anti-CD45 Antibody (3Y331) is a Mouse antibody targeting CD45. Anti-CD45 Antibody (3Y331) can be used in FCM.
AliasT200, PTPRC, LY5, L-CA, LCA, GP180, EC 3.1.3.48, CD45R, CD45, B220
Ig Type
Mouse IgG1, k
Clone
3Y331
Reactivity
Human
Verified Activity
Blank control: Molt4. Primary Antibody (green line): Mouse Anti-CD45 antibody (TMAB-00372)
Dilution: 1 μg/10^6 cells;
Isotype Control Antibody (orange line): Mouse IgG.
Secondary Antibody: Goat anti-mouse IgG-AF488
Dilution: 1 μg/test.
Protocol
The cells were incubated in 5% BSA to block non-specific protein-protein interactions for 30 min at room temperature. Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature.
Application
FCM
Recommended Dose
FCM: 1ug/Test
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular LocalizationMembrane; Single-pass type I membrane protein. Membrane raft. Note=Colocalized with DPP4 in membrane rafts.
ConstructionHybridoma Monoclonal Antibody
PurificationProtein G purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4).
Research BackgroundThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP. This gene is specifically expressed in hematopoietic cells. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling
Antigen Details
Immunogen
Recombinant Protein: human CD45
Antigen Species
Human
Gene ID
Uniprot ID
Biology Area
Endothelial Cell Markers,CD,Regulatory T Cells,CD,Non-lineage,Microglia marker,Tyrosine Phosphatases,B Lymphocytic Lineage,NK Cell Lineage,T Lymphocytic Lineage,Dendritic Cell Lineage,Mast Cell Lineage,Monocytic Lineage,Neutrophil Lineage,Surface Molecules
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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