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Anti-Evolocumab Antibody (5A316)
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Catalog No. TMAS-00041
Alias PCSK9 Inhibitor, GTPL7343, epatha, AMG-145, AMG 145
Anti-Evolocumab Antibody (5A316) is a Rabbit antibody targeting Evolocumab. Anti-Evolocumab Antibody (5A316) can be used in ELISA, Sandwich ELISA, Competitive ELISA.
Anti-Evolocumab Antibody (5A316)
Anti-Evolocumab Antibody (5A316)
😃Good
Catalog No. TMAS-00041Alias PCSK9 Inhibitor, GTPL7343, epatha, AMG-145, AMG 145
Anti-Evolocumab Antibody (5A316) is a Rabbit antibody targeting Evolocumab. Anti-Evolocumab Antibody (5A316) can be used in ELISA, Sandwich ELISA, Competitive ELISA.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 40 μg | $609 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Evolocumab Antibody (5A316) is a Rabbit antibody targeting Evolocumab. Anti-Evolocumab Antibody (5A316) can be used in ELISA, Sandwich ELISA, Competitive ELISA. |
| Synonyms | PCSK9 Inhibitor, GTPL7343, epatha, AMG-145, AMG 145 |
| Ig Type | IgG, κ |
| Clone | 5A316 |
| Specificity | Evolocumab |
| Application | |
| Recommended Dose | ELISA: 0.01-1 µg/ml; Sandwich ELISA: 0.5-2 μg/ml; Competitive ELISA: 1-10 μg/ml |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Purification | Protein A affinity column |
| Appearance | Lyophilized. Reconstitute the lyophilized powder with deionized water (or equivalent) to a final concentration of 0.5 mg/mL. |
| Formulation | Lyophilized with PBS, pH 7.2, containing 0.02% sodium azide. |
| Research Background | Evolocumab, also known as Repatha, is a monoclonal antibody used to treat hyperlipidemia through immunotherapy. This fully human monoclonal antibody works by blocking the activity of PCSK9, a protein responsible for breaking down LDL receptors. By inhibiting PCSK9, Repatha enhances the liver's capacity to remove LDL-C, commonly referred to as "bad" cholesterol, from the bloodstream. Evolocumab is the second PCSK9 inhibitor on the market, first being alirocumab. |
| Conjucates | Unconjugated |
| Immunogen | Evolocumab |
Stability & Storage
| Stability & Storage | The lyophilized product store at -20°C or -80°C for 12 months. The reconstituted antibody can be stored at 2°C-8°C for 2-3 weeks or at -20°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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