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Urocortin, human acetate (Synonyms: Urocortin, human acetate(176591-49-4 free base))

Name: Urocortin, human acetate
Brand: TargetMol
SKU: TP1021L
Rating: 4.5 (1 reviews)

Catalog No. TP1021L Copy Product Info

Purity: 96.24%

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Urocortin, human acetate is an endogenous peptide belonging to the corticotropin-releasing factor (CRF) family. By binding to and activating the CRF2 receptor with high affinity (and the CRF1 receptor moderately), it exerts critical neuroendocrine regulatory effects in modulating cardiovascular homeostasis, suppressing appetite, and mitigating stress-induced anxiety behaviors in pharmacology models.

Urocortin, human acetate

Copy Product Info

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Catalog No. TP1021L

Synonyms Urocortin, human acetate(176591-49-4 free base)

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Purity:96.24%

Appearance:Solid

Color:White

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Product Introduction

Bioactivity

Description

Synonyms

Urocortin, human acetate(176591-49-4 free base)

Chemical Properties

Molecular Weight	4757.35
Formula	C₂₀₆H₃₄₀N₆₂O₆₇
Smiles	[H]N[C@@H](CC(O)=O)C(N[C@H](C(N1CCC[C@H]1C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@]([H])(C(N[C@@H](CC(O)=O)C(N[C@H](C(N[C@]([H])(C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CC3=CN=CN3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@]([H])(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](C)C(N[C@H](C(N[C@]([H])(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](C)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@]([H])(C(N[C@]([H])(C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](CC(O)=O)C(N[C@H](C(N[C@H](C(O)=O)C(C)C)=O)CO)=O)=O)=O)[C@@H](C)CC)=O)[C@@H](C)CC)=O)CCCNC(N)=N)=O)CC(N)=O)=O)CCC(N)=O)=O)CCC(O)=O)=O)=O)CCCNC(N)=N)=O)CCC(O)=O)=O)CCCNC(N)=N)=O)CCC(N)=O)=O)CO)=O)CCC(N)=O)=O)[C@H](O)C)=O)CCCNC(N)=N)=O)=O)CC(C)C)=O)CCC(O)=O)=O)CC(C)C)=O)CC(C)C)=O)[C@H](O)C)=O)CCCNC(N)=N)=O)CC(C)C)=O)CC(C)C)=O)=O)=O)[C@H](O)C)=O)CC(C)C)=O)=O)[C@@H](C)CC)=O)CO)=O)CC(C)C)=O)CO)=O)=O)CC(N)=O)=O.CC(O)=O
Relative Density.	no data available
Sequence Short	DNPSLSIDLTFHLLRTLLELARTQSQRERAEQNRIIFDSV

Storage & Solubility Information

Storage

Keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc