Shopping Cart
Remove All
Your shopping cart is currently empty
Anti-CRTC1 Monoclonal Antibody (8P54)
(Synonyms: WAMTP1, TORC1, MECT1, KIAA0616, FLJ14027, CRTC1) Copy Product Info
😃Good
Synonyms: WAMTP1, TORC1, MECT1, KIAA0616, FLJ14027, CRTC1
Catalog No. TMAT-1394 Copy Product Info
😃Good
Anti-CRTC1 Monoclonal Antibody (8P54) is a Mouse antibody targeting CRTC1. Anti-CRTC1 Monoclonal Antibody (8P54) can be used in WB,IF,FCM.
Anti-CRTC1 Monoclonal Antibody
(8P54)
Product information is being updated, if you want to purchase, please click the bulk custom button.
Add to Quotation
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-CRTC1 Monoclonal Antibody (8P54) is a Mouse antibody targeting CRTC1. Anti-CRTC1 Monoclonal Antibody (8P54) can be used in WB,IF,FCM. |
| Synonyms | WAMTP1, TORC1, MECT1, KIAA0616, FLJ14027, CRTC1 |
| Ig Type | IgG1 |
| Clone | 8P54 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | MECT1 (also known as MucoEpidermoid Carcinoma Translocated 1) functions as a transcriptional coactivator for CREB1, which activates transcription through both consensus and variant cAMP response element (CRE) sites. MECT1 does not appear to modulate CREB1 DNA-binding activity but enhances the interaction of CREB1 with TAF4/TAFII-130. MECT1 translocates with MAML2 (MasterMind-Like Protein 2) to yield a fusion oncogene: t(11;19) (q21;p13). This translocation occurs in mucoepidermoid carcinomas, benign Warthin tumors and clear cell hidradenomas. The novel fusion product that results disrupts the Notch signaling pathway. The fusion protein consists of the N-terminus of MECT1 joined to the C-terminus of MAML2. The reciprocal fusion protein consisting of the N-terminus of MAML2 joined to the C-terminus of MECT1 has been detected in a small number of mucoepidermoid carcinomas. Multiple isoforms have been reported for the MECT1 protein. Tissue specificity: Highly expressed in adult and fetal brain. Located to specific regions such as the prefrontal cortex and cerebellum. Very low expression in other tissues such as heart, spleen, lung, skeletal muscle, salivary gland, ovary and kidney. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human CRTC1 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | CRTC1 |
| Gene ID | |
| Protein Name | CREB-regulated transcription coactivator 1 |
| Uniprot ID |
| Molecular Weight | Theoretical: 67 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Calculator
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: Anti-CRTC1 Monoclonal Antibody (8P54) molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.