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Anti-CD45 Monoclonal Antibody (9N493)
(Synonyms: T200, PTPRC, LY5, L-CA, LCA, GP180, CD45R, B220) Copy Product Info
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Synonyms: T200, PTPRC, LY5, L-CA, LCA, GP180, CD45R, B220
Catalog No. TMAT-0419 Copy Product Info
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Anti-CD45 Monoclonal Antibody (9N493) is a Mouse antibody targeting CD45. Anti-CD45 Monoclonal Antibody (9N493) can be used in IHC,FCM.
Anti-CD45 Monoclonal Antibody
(9N493)
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Product Introduction
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Related Conjugates and Formulations
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| Description | Anti-CD45 Monoclonal Antibody (9N493) is a Mouse antibody targeting CD45. Anti-CD45 Monoclonal Antibody (9N493) can be used in IHC,FCM. |
| Synonyms | T200, PTPRC, LY5, L-CA, LCA, GP180, CD45R, B220 |
| Ig Type | IgG2b |
| Clone | 9N493 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human CD45 (AA: extra 431-577) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | PTPRC |
| Gene ID | |
| Protein Name | Receptor-type tyrosine-protein phosphatase C |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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