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Ac-Leu-Arg-AMC

Name: Ac-Leu-Arg-AMC
Brand: TargetMol
SKU: TP1368
Rating: 4.5 (1 reviews)

Catalog No. TP1368 Copy Product Info

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Ac-Leu-Arg-AMC (Acetyl-Leucyl-Arginyl-7-amido-4-methylcoumarin) is a fluorogenic peptide substrate.

Ac-Leu-Arg-AMC

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Catalog No. TP1368

Ac-Leu-Arg-AMC (Acetyl-Leucyl-Arginyl-7-amido-4-methylcoumarin) is a fluorogenic peptide substrate.

Cas No. 929621-79-4

Pack Size	Price	USA Stock	Global Stock	Quantity
50 mg	Inquiry	Inquiry	Inquiry
100 mg	Inquiry	Inquiry	Inquiry

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

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Product Introduction

Bioactivity

Description

Ac-Leu-Arg-AMC (Acetyl-Leucyl-Arginyl-7-amido-4-methylcoumarin) is a fluorogenic peptide substrate.

Chemical Properties

Molecular Weight	486.56
Formula	C₂₄H₃₄N₆O₅
Cas No.	929621-79-4
Smiles	CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)Nc1ccc2c(C)cc(=O)oc2c1
Relative Density.	1.32 g/cm3 (Predicted)
Sequence	Ac-Leu-Arg-AMC
Sequence Short	LR-AMC

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 300 mg/mL (616.57 mM), Sonication and heating are recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.0552 mL	10.2762 mL	20.5524 mL	102.7622 mL
5 mM	0.4110 mL	2.0552 mL	4.1105 mL	20.5524 mL
10 mM	0.2055 mL	1.0276 mL	2.0552 mL	10.2762 mL
20 mM	0.1028 mL	0.5138 mL	1.0276 mL	5.1381 mL
50 mM	0.0411 mL	0.2055 mL	0.4110 mL	2.0552 mL
100 mM	0.0206 mL	0.1028 mL	0.2055 mL	1.0276 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Ac-Leu-Arg-AMCAcLeuArgAMCAc Leu Arg AMC