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(-)-Denudatin B (Denudatin B) is derived from Magnolia fargesii. (-)-Denudatin B has nonspecific antiplatelet action at high concentration by inhibiting phosphoinositides breakdown induced by collagen and thrombin.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $85 | - | In Stock | |
| 5 mg | $196 | - | In Stock | |
| 10 mg | $297 | - | In Stock | |
| 25 mg | $475 | - | In Stock | |
| 50 mg | Preferential | - | In Stock |
| Description | (-)-Denudatin B (Denudatin B) is derived from Magnolia fargesii. (-)-Denudatin B has nonspecific antiplatelet action at high concentration by inhibiting phosphoinositides breakdown induced by collagen and thrombin. |
| In vitro | Denudatin B inhibits the aggregation and ATP release of washed rabbit platelets caused by platelet-activating factor (PAF) in a concentration-dependent manner. High concentration of Denudatin B (greater than 50 micrograms/ml) inhibits the aggregation and ATP release of platelets caused by ADP, collagen, arachidonic acid and thrombin. Denudatin B suppresses thrombin-induced rise of the intracellular calcium concentration[1]. |
| Synonyms | Denudatin B |
| Molecular Weight | 356.41 |
| Formula | C21H24O5 |
| Cas No. | 87402-88-8 |
| Smiles | [H][C@@]1(OC2=CC(=O)C(CC=C)=C[C@@]2(OC)[C@@H]1C)c1ccc(OC)c(OC)c1 |
| Relative Density. | 1.18 g/cm3 (Predicted) |
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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