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Lamivudinetriphosphate (3TCTP) TEA is a phosphorylated form of Lamivudine, a nucleoside analogue. It inhibits the reverse transcriptase of the HIV or HBV virus, preventing viral replication through chain termination. Additionally, Lamivudine triphosphate TEA is an inhibitor of RdRp activity in the HCV NS5B subunit. It can also be incorporated into nascent RNA by SARS-CoV-2 RdRp, thereby halting mutations in new SARS-CoV-2 RNA.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry | Inquiry |
| Description | Lamivudinetriphosphate (3TCTP) TEA is a phosphorylated form of Lamivudine, a nucleoside analogue. It inhibits the reverse transcriptase of the HIV or HBV virus, preventing viral replication through chain termination. Additionally, Lamivudine triphosphate TEA is an inhibitor of RdRp activity in the HCV NS5B subunit. It can also be incorporated into nascent RNA by SARS-CoV-2 RdRp, thereby halting mutations in new SARS-CoV-2 RNA. |
| Synonyms | 3TCTP TEA |
| Molecular Weight | 772.77 |
| Formula | C26H59N6O12P3S |
| Cas No. | 2736455-56-2 |
| Smiles | CCN(CC)CC.O=C1N([C@H]2O[C@H](SC2)COP(OP(OP(O)(O)=O)(O)=O)(O)=O)C=CC(N)=N1.CCN(CC)CC.CCN(CC)CC |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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