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Flagelin 22 TFA (304642-91-9 free base)

(Synonyms: Flagelin 22 TFA (304642-91-9 free base)) Copy Product Info
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Synonyms: Flagelin 22 TFA (304642-91-9 free base)

Catalog No. TP1169 Copy Product Info
Purity: 99.26%
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Flagelin 22 TFA, a fragment derived from bacterial flagellin, functions as an effective elicitor in both plants and algae. Flagelin 22 TFA is relevant for investigations involving innate immune signaling, plant-pathogen interactions, algal defense mechanisms, and pattern-recognition receptor activation.
Flagelin 22 TFA (304642-91-9 free base)
Pack SizePriceUSA StockGlobal StockQuantity
1 mg$98-In Stock
5 mg$319-In Stock
10 mg$504-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.26%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
Flagelin 22 TFA, a fragment derived from bacterial flagellin, functions as an effective elicitor in both plants and algae. Flagelin 22 TFA is relevant for investigations involving innate immune signaling, plant-pathogen interactions, algal defense mechanisms, and pattern-recognition receptor activation.
In vitro
Flagelin 22 TFA (free base) (100 nM, 1 or 24 h) activates pattern-triggered immunity (PTI)-related gene expression and leads to reduced expression of brassinolide (BR) biosynthesis genes involved in plant growth promotion [1].
Flagelin 22 TFA (free base) (10 μM, 4 h) regulates the release of ethylene response factor substrates through ethylene signaling in Arabidopsis MAP kinase 6[2].
SynonymsFlagelin 22 TFA (304642-91-9 free base)
Chemical Properties
Molecular Weight2386.53
FormulaC95H163F3O36N32
SmilesNC(CC[C@H](N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(N[C@@H]([C@H](O)C)C(NCC(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(N)=O)C(N[C@@H](CO)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](C)C(N[C@@H](C)C(NCC(N[C@@H](CC(C)C)C(N[C@@H](CCC(N)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O
Relative Density.no data available
SequenceGln-Arg-Leu-Ser-Thr-Gly-Ser-Arg-Ile-Asn-Ser-Ala-Lys-Asp-Asp-Ala-Ala-Gly-Leu-Gln-Ile-Ala
Sequence ShortQRLSTGSRINSAKDDAAGLQIA
Storage & Solubility Information
StorageKeep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (33.52 mM), Sonication is recommended.
H2O: 26 mg/mL (10.89 mM), Sonication is recommended.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM0.4190 mL2.0951 mL4.1902 mL20.9509 mL
5 mM0.0838 mL0.4190 mL0.8380 mL4.1902 mL
10 mM0.0419 mL0.2095 mL0.4190 mL2.0951 mL
DMSO
1mg5mg10mg50mg
20 mM0.0210 mL0.1048 mL0.2095 mL1.0475 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 µL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
µL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: Flagelin 22 TFA (304642-91-9 free base) chemical structure | Flagelin 22 TFA (304642-91-9 free base) in vitro | Flagelin 22 TFA (304642-91-9 free base) formula | Flagelin 22 TFA (304642-91-9 free base) molecular weight