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Selective PAR2 peptide antagonist. Reverses taxol-induced mechanical allodynia, heat hyperalgesia and PKC activation in ICR mice. Blocks ERK activation and collagen production in isolated cardiac fibroblasts. Also reduces symptoms in a mouse model of dermatophyte-associated itch.

| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $323 | 35 days | |
| 5 mg | $855 | 35 days | |
| 10 mg | $1,430 | 35 days | |
| 25 mg | $2,760 | 35 days |
| Description | Selective PAR2 peptide antagonist. Reverses taxol-induced mechanical allodynia, heat hyperalgesia and PKC activation in ICR mice. Blocks ERK activation and collagen production in isolated cardiac fibroblasts. Also reduces symptoms in a mouse model of dermatophyte-associated itch. |
| Molecular Weight | 796.97 |
| Formula | C39H60N10O8 |
| Cas No. | 245329-02-6 |
| Relative Density. | no data available |
| Sequence | Phe-Ser-Leu-Leu-Arg-Tyr-NH2 |
| Sequence Short | FSLLRY-NH2 |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||
| Solubility Information | H2O: 1 mg/mL (1.25 mM), Sonication is recommended. | ||||||||||
Solution Preparation Table | |||||||||||
H2O
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