Sarafotoxin S6a

Name: Sarafotoxin S6a
Brand: TargetMol
SKU: TP2119
Rating: 4.5 (1 reviews)

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Catalog No. TP2119Cas No. 126738-34-9

Endothelin receptor agonist (EC50 values are 7.5 and > 150 nM for contraction of pig coronary artery and guinea pig aorta respectively). Nociceptive in vivo.

Sarafotoxin S6a

😃Good

Catalog No. TP2119Cas No. 126738-34-9

Endothelin receptor agonist (EC50 values are 7.5 and > 150 nM for contraction of pig coronary artery and guinea pig aorta respectively). Nociceptive in vivo.

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1 mg	$539	Inquiry	Inquiry

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Product Introduction

Bioactivity

Description

Endothelin receptor agonist (EC50 values are 7.5 and > 150 nM for contraction of pig coronary artery and guinea pig aorta respectively). Nociceptive in vivo.

Chemical Properties

Molecular Weight	2514.85
Formula	C₁₀₅H₁₅₆N₂₈O₃₄S₅
Cas No.	126738-34-9
Smiles	C([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CN=CN1)NC(=O)[C@H]2NC(=O)[C@H](CC3=CC=CC=C3)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@]4(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@]([C@@H](C)O)(NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@](NC(=O)[C@H](CO)NC(=O)[C@@H](N)CSSC2)(CSSC4)[H])[H])[H])=O)CCC(N)=O)=O)CC(O)=O)=O)C(C)C)=O)[C@H](CC)C)=O)C(O)=O)C=5C=6C(NC5)=CC=CC6
Relative Density.	1.298 g/cm3 (Predicted)
Sequence	Cys-Ser-Cys-Lys-Asp-Met-Thr-Asp-Lys-Glu-Cys-Leu-Asn-Phe-Cys-His-Gln-Asp-Val-Ile-Trp (Disulfide bridge:Cys1-Cys15;Cys3-Cys11)
Sequence Short	CSCKDMTDKECLNFCHQDVIW (Disulfide bridge:Cys1-Cys15;Cys3-Cys11)

Storage & Solubility Information

Storage	keep away from moisture \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	H2O: 1 mg/mL (0.4 mM), Sonication is recommended.

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline /PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Stock solution preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline /PBS/ddH₂O TargetMol | reagent

mix well and clarify

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