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Anti-TERT Monoclonal Antibody (9A608)
(Synonyms: TRT, TP2, TCS1, PFBMFT1, hTRT, hEST2, EST2, DKCB4, DKCA2, CMM9) Copy Product Info
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Synonyms: TRT, TP2, TCS1, PFBMFT1, hTRT, hEST2, EST2, DKCB4, DKCA2, CMM9
Catalog No. TMAT-0595 Copy Product Info
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Anti-TERT Monoclonal Antibody (9A608) is a Mouse antibody targeting TERT. Anti-TERT Monoclonal Antibody (9A608) can be used in IHC,FCM.
Anti-TERT Monoclonal Antibody
(9A608)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Stability & Storage
| Description | Anti-TERT Monoclonal Antibody (9A608) is a Mouse antibody targeting TERT. Anti-TERT Monoclonal Antibody (9A608) can be used in IHC,FCM. |
| Synonyms | TRT, TP2, TCS1, PFBMFT1, hTRT, hEST2, EST2, DKCB4, DKCA2, CMM9 |
| Ig Type | IgG1 |
| Clone | 9A608 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified; the full-length sequence of some variants has not been determined. Alternative splicing at this locus is thought to be one mechanism of regulation of telomerase activity. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human TERT (AA: 1029-1132) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | TERT |
| Gene ID | |
| Protein Name | Telomerase reverse transcriptase |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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